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GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I

CODE 80319
ACADEMIC YEAR 2017/2018
CREDITS 12 credits during the 3nd year of 8452 Pharmacy (LM-13) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR CHIM/08
LANGUAGE Italian
TEACHING LOCATION GENOVA (Pharmacy)
PREREQUISITES
Prerequisites
You can take the exam for this unit if you passed the following exam(s):
  • Pharmacy 8452 (coorte 2015/2016)
  • GENERAL AND INORGANIC CHEMISTRY (PHAR)(MD) 55413
  • ORGANIC CHEMISTRY 60795
Prerequisites (for future units)
This unit is a prerequisite for:
  • Pharmacy 8452 (coorte 2015/2016)
  • MEDICINAL CHEMISTRY AND TOXICOLOGICAL CHEMISTRY 80337
  • PHARMACEUTICAL TECHNOLOGY, SOCIOECONOMY AND LAW II (PHAR MD) 67522
  • PHARMACEUTICAL TECHNOLOGY SOCIOECONOMY AND LAW I (WITH PRACTICE) 67449
MODULES This unit is composed by:

OVERVIEW

The drug-discovery process as well as the structure-activity relationships of the different classes of chemotherapeutic agents and hormones (peptide and steroidal) are presented in the course

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course aims at presenting the relevant approaches currently used in the drug discovery process and the structure-activity relationships developed for chemotherapeutic agents (i.e. antibacterial, antiviral and antitumor agents) and for steroidal/peptide hormones. This knowledge is part of the cultural background characterizing a pharmacist as an healthcare professional.

TEACHING METHODS

Lectures

SYLLABUS/CONTENT

The first part of the course is focussed on the drug discovery process with particular emphasis on computer aided drug design and combinatorial chemistry.

The second part deals with the synthetic strategies, the structure-activity relationships and the pharmacokinetic/pharmacodynamic properties of different classes of chemotherapeutic drugs (e.g. antibacterial, antiprotozoal, antimycotic, antiviral and antitumor agents) and steroidal/peptide hormones.

RECOMMENDED READING/BIBLIOGRAPHY

Foye's. Principi di chimica farmaceutica. Piccin

Wilson & Gisvold. Chimica Farmaceutica. Casa Editrice Ambrosiana

Gasco, Gualtieri, Melchiorre. Chimica faramceutica. Casa Editrice Ambrosiana

TEACHERS AND EXAM BOARD

Exam Board

ANDREA SPALLAROSSA (President)

CHIARA BRULLO

FRANCESCA MUSUMECI

SILVIA SCHENONE

BRUNO TASSO

LESSONS

TEACHING METHODS

Lectures

Class schedule

All class schedules are posted on the EasyAcademy portal.

EXAMS

EXAM DESCRIPTION

Oral examination

ASSESSMENT METHODS

The exam is directed to the evaluation of the learning, the communicative and problem-solving skills of the student

Exam schedule

Date Time Location Type Notes
04/04/2018 09:00 GENOVA Orale
13/06/2018 09:00 GENOVA Orale
04/07/2018 09:00 GENOVA Orale
25/07/2018 09:00 GENOVA Orale
04/09/2018 09:00 GENOVA Orale
18/09/2018 09:00 GENOVA Orale
23/01/2019 09:00 GENOVA Orale
14/02/2019 09:00 GENOVA Orale
04/04/2018 09:00 GENOVA Orale
13/06/2018 09:00 GENOVA Orale
04/07/2018 09:00 GENOVA Orale
25/07/2018 09:00 GENOVA Orale
04/09/2018 09:00 GENOVA Orale
18/09/2018 09:00 GENOVA Orale
23/01/2019 09:00 GENOVA Orale
14/02/2019 09:00 GENOVA Orale