| CODE | 80678 |
|---|---|
| ACADEMIC YEAR | 2017/2018 |
| CREDITS | 4 credits during the 2nd year of 9015 Molecular and health biology (LM-6) GENOVA |
| SCIENTIFIC DISCIPLINARY SECTOR | BIO/12 |
| LANGUAGE | Italian (English on demand) |
| TEACHING LOCATION | GENOVA (Molecular and health biology) |
| SEMESTER | 2° Semester |
| PREREQUISITES |
Prerequisites
You can take the exam for this unit if you passed the following exam(s):
|
Clinical biochemistry studies the clinical significance of laboratory tests. During the course we will systematically address the study of laboratory medicine of the main organs and functions, which is a a key part of the diagnostic reasoning process.
The aim of the clinical biochemistry part of the course is to allow the student to acquire basic knowledge on the clinical-diagnostic significance of the laboratory tests of the “clinical chemistry profile” and of specific organs/functions. This knowledge will be applied to the discussion of simple case-studies, allowing the students to put into practice the basic knowledge acquired and test their understanding of laboratory tests.
The aim of the clinical biochemistry part of the course is to allow the student to acquire basic knowledge on the clinical-diagnostic significance of the laboratory tests of the “clinical chemistry profile” and of specific organs/functions. This knowledge will be applied to the discussion of simple case-studies, allowing the students to put into practice the basic knowledge acquired and test their understanding of laboratory tests.
plenary lectures.
A minimal attendance to 70% of the plenary lectures is strongly recommended.
1-BLOOD
The complete blood count
Electrophoretic profile of serum proteins and its diagnostic interpretation
Principal serum enzymes of diagnostic interest
Non-protein nitrogen
Iron metabolism, quantitative and qualitative defects of hemoglobin
Electrolytes
2-LIVER FUNCTION
Enzymes, bilirubin and jaundice, modifications of serum proteins in selected liver diseases, coagulation factors, diagnosis of selected liver diseases
3-GLUCOSE METABOLISM
Hormones regulating glycemia
Causes of hyper- and hypo-glycemia
Lab tests in diabetes mellitus
Lab tests in chetoacidosis, glucose tolerance test, gestational diabetes.
4-LIPID METABOLISM
Lipoprotein classification and function
Reference values for blood lipids
Hyperlipidemic profiles and cardiovascular risk
5-URINE ANALYSIS AND TESTS OF RENAL FUNCTION
The physical-chemical urineanalysis
Renal functional tests: indicators of glomerular and tubular malfunction
6-TESTS FOR ENDOCRINE DISORDERS
Steroid, peptide and aminoacid-derived hormones: basal levels and pathologic conditions of hyper/hypo-secretion
Lab tests in the diagnosis of endocrinological disorders
7- LAB CONFIRMATION OF ACUTE MYOCARDIAL INFARCTION
8-TESTS OF PANCREATIC FUNCTION
9-ARTERIAL BLOOD GASES AND ACID-BASE BALANCE
10-VITAMINS
11-ELECTROLYTE BALANCE
online available slides (aula-web)
Common laboratory tests, Vaughn, Appleton&Lange
Office hours: upon appointment by e-mail
ELENA ZOCCHI (President)
SANTINA BRUZZONE
LAURA STURLA
plenary lectures.
A minimal attendance to 70% of the plenary lectures is strongly recommended.
arranged with the students
All class schedules are posted on the EasyAcademy portal.
Knowledge acquired by the students will be verified with a written test.
A multiple choice tests will ascertain whether the student will have acquired a sufficient knowledge ragarding the topics dealt with during the course.