| CODE | 67362 |
|---|---|
| ACADEMIC YEAR | 2017/2018 |
| CREDITS | 8 credits during the 3nd year of 8745 MEDICINE AND SURGERY (LM-41) GENOVA |
| SCIENTIFIC DISCIPLINARY SECTOR | MED/04 |
| LANGUAGE | Italian |
| TEACHING LOCATION | GENOVA (MEDICINE AND SURGERY) |
| SEMESTER | 1° Semester |
| PREREQUISITES |
Prerequisites
You can take the exam for this unit if you passed the following exam(s):
Prerequisites (for future units)
This unit is a prerequisite for:
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The course gives students the fundamental elements of pathophysiology, which are essential for the successive comprehension of clinical medical sciences.
Physiopathology is a branch of medicine that combines physiology and pathology especially in the study of altered bodily function in disease. The learning outcome is the knowledge of the main physiopathological mechanisms of organs and systems, in order to recognize the mechanisms and causes of their malfunction, and to be able to interpret the symptoms, which will be exposed to the students in the successive clinical courses
Knowledge of the main physiopathological mechanisms of organs and systems, with particular regard to blood, liver, kidney, respiratory and digestive systems, some aspects of endocrinology and metabolism, and the physiopathology of neoplasms.
Lectures, with any possible dialectic interaction with students
Hematopoiesis, hematopoietic stem cell (HSC), mesenchimal stem cell (MSC), HSC transplant (HSCT).
Erythropoiesis, classification and examples of anemia: aplastic, paroxysmal nocturnal nemoglobinuria (PNH), immune hemolytic, deficiency (Fe, B12 and B9), drugs-mediated, secondary to chronic disorders.
Hemostasis and examples of hemostasis disorders (endothelium, platelets or coagulation factors abnormalities).
Oncology: benign and malign neoplasms, metastasis, local and systemic effects, paraneoplastic syndromes. Epidemiology (risk and prognostic factors). Molecular basis of tumor transformation: oncogenes, oncosuppressors and examples of tumors. Epigenetic mechanisms (methylation, miRNA). Hematological malignances: classification and examples of myeloid and lymphoid neoplasms. Cancer stem cells (CSC), Tumor-associated angiogenesis and tumor microenvironment. Immune responses against cancer, tumor escape mechanisms, tumor-associated inflammation.
Pathogenesis and consequences of dyslipidemias. Atherosclerosis, cardiovascular diseases, Acute rheumatic fever (ARF), essential and secondary hypertension.
Classification of renal diseases, and acute and chronic renal failure. Hydro-electrolytic balance, in particular sodium and potassium. Acid base balance and its alterations.
Pathogenesis and pathophysiology of diabetes mellitus.
Pathophysiology of the respiratory system.
Pathophysiology of the liver and the biliary tract: acute and chronic hepatitis, cirrhosis and ascites, hepatic failure, portal hypertension, cholestasis, icterus, systemic effects of liver damage
Liver metabolic diseases: Alpha-1 antitrypsin deficiency
Hemochromatosis and Hemosiderosis
Wilson disease
Overview of most common digestive disorders
Overview of most common pancreatic disorders
Robbins & Cotran Pathologic Basis of Disease, Elsevier
The didactic material is available in pdf format for download (https://www.aulaweb.unige.it). The aim of the course is also to familiarize students with online biomedical scientific literature (https://www.ncbi.nlm.nih.gov/pubmed)
Office hours: By appointment Email: Cristina.Bottino@unige.it
Office hours: Students can contact the teachers by mail
Office hours: By appointment by email: ntravers@medicina.unige.it o Nicola.Traverso@unige.it
CRISTINA BOTTINO (President)
MARIA ADELAIDE PRONZATO (President)
NICOLA TRAVERSO (President)
ANNA MARIA BASSI
CINZIA MARIA DOMENICOTTI
Lectures, with any possible dialectic interaction with students
1st semester, 3rd year
All class schedules are posted on the EasyAcademy portal.
The students are evaluated in an oral examination. Two professors examine each student about any of the subject of the course program.
The oral examination consists in several questions, starting from more general questions to more precise ones, in order to assess the knowledge of the students. Students must know the main physiopathological mechanisms of the selected organs/systems and demonstrate the ability to connect different subjects of the program.
| Date | Time | Location | Type | Notes |
|---|---|---|---|---|
| 15/01/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 29/01/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 12/02/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 09/04/2018 | 09:00 | GENOVA | Orale | APPELLO RISERVATO A STUDENTI FUORICORSO SENZA OBBLIGO DI FREQUENZA ORE 9, AULA PATOLOGIA GENERALE |
| 04/06/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 18/06/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA FISIOLOGIA |
| 09/07/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 10/09/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 24/09/2018 | 09:00 | GENOVA | Orale | ORE 9, AULA PATOLOGIA GENERALE |
| 12/11/2018 | 09:00 | GENOVA | Orale | ore 9, Aula patologia generale Appello riservato a studenti fuoricorso o ripetenti SENZA OBBLIGO DI FREQUENZA |
The didactic material is available in pdf format for download (https://www.aulaweb.unige.it)
Students can contact the teachers by mail (information, appointment)