AIMS AND LEARNING OUTCOMES

Knowledge of fundamental and additional structures, peculiar of bacteria, as extrinsic cause of disease in general, infectious in particular. Knowledge how bacteria cause to cells and human organism damage, toxic, inflammatory and inhibiting immune surveillance. Knowledge of structure of human viruses and their pathogenicity. Knowledge of antibacterial drugs. Knowledge of the main lines of microbiological diagnostics, direct and indirect.

PREREQUISITES

Basic knowledge acquired with the frequency of the lessons of the courses included in the study plan.
The study plan is structured so as to allow a gradual acquisition of knowledge and skills in the main subjects under study.

TEACHING METHODS

The course consists of 10 hours of classroom lessons on all topics of the program.
The lessons are delivered with Power Point presentations

SYLLABUS/CONTENT

1) fundamental differences between multicellular organisms and microorganisms and between prokaryotic and eukaryotic cell, fundamental and accessory structures of bacterial cells
2) peculiar genetic and metabolism of the bacterial cell, bacterial spores in general and spore-forming bacteria as cause of human diseases
3) the difference between saprophytic bacteria and parasites, exogenous and endogenous infections, direct and indirect mechanisms of bacterial pathogenicity
4) general microbiological diagnosis, direct and indirect (serology), bacteriological diagnosis, antibacterial drugs, bacterial resistance to drugs, genetic mechanisms of onset of resistance and phenotypes
5) structure of viruses in general and DNA and RNA viruses in particular, viral replication and pathogenesis, virology diagnosis, direct and indirect.

RECOMMENDED READING/BIBLIOGRAPHY

All the topics covered in class can be found in the ”aula web” With digital support, students are given by slides shown in class and handouts prepared by the teacher, summary of lessons provided and available in Aula Web (https://www.aulaweb.unige.it)

Any other more in-depth material is mentioned at the end of the lesson in the “aula web” slides and described in the following textbook

Microbiologia: P. Cipriani, G. Dicuonzo

 “Elementi di Microbiologia e Microbiologia Clinica” McGraw-Hill Editore