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BIOCHEMISTRY

CODE 58031
ACADEMIC YEAR 2018/2019
CREDITS 10 credits during the 1st year of 8745 MEDICINE AND SURGERY (LM-41) GENOVA
SCIENTIFIC DISCIPLINARY SECTOR BIO/10
LANGUAGE Italian
TEACHING LOCATION GENOVA (MEDICINE AND SURGERY)
SEMESTER 2° Semester
MODULES This unit is a module of:
TEACHING MATERIALS AULAWEB

OVERVIEW

Biochemistry, together with molecular biology and human genetics, is necessary to understand the molecular events underlying human physiology and pathology. This Course will teach the basic mechanisms of chemical and metabolic modifications in order to understand the molecular basis of diseases.

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

At the end of this course, the student must have acquired an understanding of the biochemical reactions of the major anabolic and catabolic pathways, and of their relevance to understand the molecular basis of disease. 

TEACHING METHODS

Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together.

SYLLABUS/CONTENT

Proteins: composition and structure (Teacher Prof. Santina Bruzzone)

Proteins:structure-function relationships in protein families (Teacher Prof. Santina Bruzzone)

Enzymes: classification kinetics and control (Teacher Prof. Santina Bruzzone)

Bioenergetics and oxidative metabolism (Teacher Prof. Santina Bruzzone)

Carbohydrate metabolism: major metabolism and their control (Teacher Prof. Michela Tonetti)

Carbohydrate metabolism: special pathways (Teacher Prof. Michela Tonetti)

Lipid metabolism: transport, utilization and storage of energy in lipid form (Teacher Prof. Santina Bruzzone)

Lipid metabolism: pathways of metabolism of special lipids (Teacher Prof. Santina Bruzzone)

Aminoacid metabolism (Teacher Prof. Elena Zocchi)

Purine and pyrimidine nucleotide metabolism: metabolic interrelationships (Teacher Prof. Elena Zocchi)

Biochemistry of hormones: polypeptide hormones(Teacher Prof. Elena Zocchi) 

Biochemistry of hormones: steroid hormones (Teacher Prof. Elena Zocchi)

Biochemistry of liver, muscle and adipose tissue (Teacher Prof. Elena Zocchi)

Iron and heme metabolism (Teacher Prof. Santina Bruzzone)

Principle of nutrition: water soluble vitamins and lipid soluble vitamin(Teacher Prof. Michela Tonetti) 

RECOMMENDED READING/BIBLIOGRAPHY

Materials published in Aula Web

Texbook:

Nelson and Cox: Lehninger Principles of Biochemistry w.h. freeman ed.

Devlin: Textbook of biochemistry with clinical correlations Wiley-Liss ed

TEACHERS AND EXAM BOARD

Exam Board

SANTINA BRUZZONE (President)

GIANLUCA DAMONTE (President)

MICHELA TONETTI

ELENA ZOCCHI (President and Coordinator of Integrated Course)

LESSONS

TEACHING METHODS

Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together.

LESSONS START

6 march 2017 

Class schedule

All class schedules are posted on the EasyAcademy portal.

EXAMS

EXAM DESCRIPTION

Oral exam. Students should pass the Biochemistry 1 test before enlisting for the  Biochemistry 2 oral exam. The final score will include both subjects.

ASSESSMENT METHODS

The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes.

Exam evaluation will take into account knowledge, presentation/speaking skills, as well as the ability in connecting the different arguments.

Exam schedule

Date Time Location Type Notes
11/01/2019 09:30 GENOVA Orale
25/01/2019 15:00 GENOVA Scritto
30/01/2019 09:30 GENOVA Orale
15/02/2019 15:00 GENOVA Scritto
27/02/2019 09:30 GENOVA Orale
01/03/2019 15:00 GENOVA Scritto
05/06/2019 09:30 GENOVA Orale
07/06/2019 15:00 GENOVA Scritto
19/06/2019 09:30 GENOVA Orale
28/06/2019 15:00 GENOVA Scritto
03/07/2019 09:30 GENOVA Orale
12/07/2019 15:00 GENOVA Scritto
24/07/2019 09:30 GENOVA Orale
20/09/2019 15:00 GENOVA Scritto
25/09/2019 09:30 GENOVA Orale