Salta al contenuto principale della pagina

MICROBIOLOGY AND CLINICAL MICROBIOLOGY

CODE 62664
ACADEMIC YEAR 2020/2021
CREDITS
  • 6 cfu during the 2nd year of 8746 ODONTOIATRIA E PROTESI DENTARIA (LM-46) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR MED/07
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 1° Semester
    MODULES This unit is a module of:
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    Microorganisms have an extraordinary impact on the entire life and the composition of our planet. Microorganisms and humans have a very close relationship. 
    Some thousands of microbial species, collectively known as microbiota, live in our body and plays useful functions, while other species, pathogens, may cause morbidity. Upon the completion of this course the students should know the biology of the microorganisms and their strategies to cause diseases in humans and in particular in oral cavity

    AIMS AND CONTENT

    LEARNING OUTCOMES

    General Microbiology: To know the main characteristics of prokaryotes, eukaryotes and viruses and their classification. The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease).
    General Bacteriology: To know the characteristics of bacteria (bacterial structure, growth and microbial metabolism, overview of bacterial genetics). To understand the bacterial pathogenicity and virulence factors (input, adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antiphagocytic mechanisms), intracellular parasites and heterogeneity antigen. To know the major classes of chemotherapeutic agents and antibiotics (beta-lactams, glycopeptides, aminoglycosides, tetracyclines, quinolones, chloramphenicol, macrolides, clindamycin, oxazolidinones, streptogramins, nitroimidazoles, rifampin) and their main characteristics (spectrum of action, target, pharmacokinetics and mechanisms of drug resistance). Susceptibility and antimicrobial resistance  and quantitative and qualitative determination of antibiotic activity. 

    General Virology: To know the general characteristics of the viruses (structure and composition,  viral classification, viral replication, viral genetics overview). To understand the mechanism of viral penetration into the host,  viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation). To know the antiviral drugs and resistances.
    Mycology a: To know the general characteristics of pathogenic fungi 
    Oral Microbiology: to know the chracteristics of the oral ecosystem, oral microbiota and the pathogenicity mechanisms causing caries, gengivitis, parodontitis...

    TEACHING METHODS

    lessons for 60 hours in classroom. Compulsory class attendance.

    SYLLABUS/CONTENT

    -Main characteristics of prokaryotes, eukaryotes and viruses and their classification.
     -The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease).
     - Characteristics of bacteria (bacterial structure, growth and bacterial metabolism, overview of bacterial genetics) .
    -Bacterial pathogenicity and virulence factors (input, adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antifagocitari mechanisms).
    -Intracellular parasites and heterogeneity antigen.
    -Classification of antibiotics (beta-lactams, glycopeptides, aminoglycosides, tetracyclines, quinolones, chloramphenicol, macrolides, clindamycin, oxazolidinones, streptogramins, nitroimidazoles, rifampin). 
    -Antibiotics: spectrum of activity, target, pharmacokinetics and mechanisms of drug resistance. Susceptibility and antimicrobial resistance  and quantitative and qualitative determination of antibiotic activity.  
    - General characteristics of viruses (structure and composition, viral classification, viral replication, viral genetics overview). 
    -Mechanism of viral penetration into the host, viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation). Antiviral drugs and resistances.
    - General characteristics of pathogenic fungi.

    -Oral microbiology: oral ecosystem, microbioma, the role of microorganisms in tha major infective oral disease: caries, gengivitis, parodontitis...

     

    RECOMMENDED READING/BIBLIOGRAPHY

    Microbiologia: AA.VV. Principi di microbiologia Medica. Casa Editrice Ambrosiana

    TEACHERS AND EXAM BOARD

    Exam Board

    ANNA MARCHESE (President)

    CECILIA TRUCCHI (President)

    CARLO PESCE

    DANIELA AMICIZIA (President and Coordinator of Integrated Course)

    LESSONS

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    written test

    ASSESSMENT METHODS

    The evaluation is carried out through the only final exam which seeks to ascertain the actual acquisition by the student of the expected learning results. To demonstrate their knowledge, the students will be able to know:
    -the main characteristics of prokaryotes, eukaryotes and viruses and their classification. The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease); 
    -the characteristics of bacteria (bacterial structure, growth and microbial metabolism, overview of bacterial genetics);
    -the bacterial pathogenicity and virulence factors (input, adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antiphagocytic mechanisms), intracellular parasites and heterogeneity antigen;
    -the major classes of chemotherapeutic agents and antibiotics (beta-lactams, glycopeptides, aminoglycosides, tetracyclines, quinolones, chloramphenicol, macrolides, clindamycin, oxazolidinones, streptogramins, nitroimidazoles, rifampin) and their main characteristics (spectrum of action, target, pharmacokinetics and mechanisms of drug resistance); 
    -susceptibility and antimicrobial resistance  and quantitative and qualitative determination of antibiotic activity;
    -the general characteristics of the viruses (structure and composition,  viral classification, viral replication, viral genetics overview);
    -the mechanism of viral penetration into the host,  viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation);
    -the antiviral drugs and resistances;
    -the general characteristics of pathogenic fungi

    -the characteristics of the main species causing human infectious diseases.

    -the microbiology of the oral cavity: microbiota and pathogens
    A minimum mark of 18/30 is required to pass the module. The mark 30/30 with any honors will correspond to an excellent knowledge of all argoments.

     

    Exam schedule

    Date Time Location Type Notes
    11/01/2021 15:00 GENOVA Scritto + Orale
    05/02/2021 15:00 GENOVA Scritto + Orale
    09/03/2021 08:30 GENOVA Scritto + Orale Microbiologia ore 8:30 Igiene ore 15:00
    04/06/2021 15:00 GENOVA Scritto + Orale
    09/07/2021 15:00 GENOVA Scritto + Orale