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GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I

CODE 80319
ACADEMIC YEAR 2021/2022
CREDITS
  • 12 cfu during the 3nd year of 8452 FARMACIA (LM-13) - GENOVA
    		•
    SCIENTIFIC DISCIPLINARY SECTOR CHIM/08
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
    		•
    PREREQUISITES
    Prerequisites
    You can take the exam for this unit if you passed the following exam(s):
    • Pharmacy 8452 (coorte 2019/2020)
    • GENERAL AND INORGANIC CHEMISTRY (PHAR)(MD) 55413
    • ORGANIC CHEMISTRY 60795
    Prerequisites (for future units)
    This unit is a prerequisite for:
    • Pharmacy 8452 (coorte 2019/2020)
    • MEDICINAL CHEMISTRY AND TOXICOLOGICAL CHEMISTRY 80337
    • PHARMACEUTICAL TECHNOLOGY, SOCIOECONOMY AND LAW II (PHAR MD) 67522
    • PHARMACEUTICAL TECHNOLOGY SOCIOECONOMY AND LAW I (WITH PRACTICE) 67449
    MODULES This unit is composed by:
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    The drug-discovery process as well as the structure-activity relationships of the different classes of chemotherapeutic agents and hormones (peptide and steroidal) are presented in the course

    AIMS AND CONTENT

    AIMS AND LEARNING OUTCOMES

    The course aims at presenting the relevant approaches currently used in the drug discovery process and the structure-activity relationships developed for chemotherapeutic agents (i.e. antibacterial, antiviral and antitumor agents) and for steroidal/peptide hormones. This knowledge is part of the cultural background characterizing a pharmacist as an healthcare professional.

    TEACHING METHODS

    Lectures

    SYLLABUS/CONTENT

    The first part of the course is focussed on the drug discovery process with particular emphasis on computer aided drug design and combinatorial chemistry.

    The second part deals with the synthetic strategies, the structure-activity relationships and the pharmacokinetic/pharmacodynamic properties of different classes of chemotherapeutic drugs (e.g. antibacterial, antiprotozoal, antimycotic, antiviral and antitumor agents) and steroidal/peptide hormones.

    RECOMMENDED READING/BIBLIOGRAPHY

    Foye's. Principi di chimica farmaceutica. Piccin

    Wilson & Gisvold. Chimica Farmaceutica. Casa Editrice Ambrosiana

    Gasco, Gualtieri, Melchiorre. Chimica faramceutica. Casa Editrice Ambrosiana

    TEACHERS AND EXAM BOARD

    Exam Board

    ANDREA SPALLAROSSA (President)

    CHIARA BRULLO

    FRANCESCA MUSUMECI

    SILVIA SCHENONE

    BRUNO TASSO

    LESSONS

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    Viva oral examination

    ASSESSMENT METHODS

    The exam is directed to the evaluation of the learning, the communicative and problem-solving skills of the student

    Exam schedule

    Date Time Location Type Notes
    21/06/2022 09:00 GENOVA Orale
    04/07/2022 09:00 GENOVA Orale
    18/07/2022 09:00 GENOVA Orale
    05/09/2022 09:00 GENOVA Orale
    19/09/2022 09:00 GENOVA Orale
    23/01/2023 09:00 GENOVA Orale
    15/02/2023 09:00 GENOVA Orale
    21/06/2022 09:00 GENOVA Orale
    04/07/2022 09:00 GENOVA Orale
    18/07/2022 09:00 GENOVA Orale
    05/09/2022 09:00 GENOVA Orale
    19/09/2022 09:00 GENOVA Orale
    23/01/2023 09:00 GENOVA Orale
    15/02/2023 09:00 GENOVA Orale