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PHARMACOLOGY

CODE 67210
ACADEMIC YEAR 2021/2022
CREDITS
  • 6 cfu during the 3nd year of 8746 ODONTOIATRIA E PROTESI DENTARIA (LM-46) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR BIO/14
    LANGUAGE Italian
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 2° Semester
    PREREQUISITES
    Prerequisites
    You can take the exam for this unit if you passed the following exam(s):
    • School of Dental Medicine 8746 (coorte 2019/2020)
    • EXPERIMENTAL PATHOLOGY 62662
    Prerequisites (for future units)
    This unit is a prerequisite for:
    • School of Dental Medicine 8746 (coorte 2019/2020)
    • MEDICAL SCIENCES II 67223
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    Pharmacology is the science that study the interactions between the drugs and the body. This include the study of the origin and the chemical structure of the drugs, the molecular mechanisms the mediate their effects inthe the body, the pharmacokinetics, their clinical use, their toxicity, and the adverse reactions that they can determine.

    AIMS AND CONTENT

    LEARNING OUTCOMES

    The aim of this course is to provide the students with knowledge about fundamental concepts of the main pharmacological classes required to be able to administer the drugs commonly used during the odontoiatric practice, including their composition therapeutic effects and ADRs. Furthermore the student have to learn the effects, contraindications and adverse reactions of drugs prescribed to the patients that could interfere with his paractice and the knowledge of the drugs used in emergency.

    AIMS AND LEARNING OUTCOMES

    The main learning outcome of the Pharmacology course is acquisition of all the basic information required to be able to prescribe and administer the relevant drugs for the Odontoiatric practice, including mechanism of action, therapeutic indications, ADRs, and contraindications.

    In detail the student have to get knowledge on:

    the molecular and cellular targets that mediate the drug therapeutic and adverse effects;

    administration modality and the fate of the drugs within the body, inclding the mechanisms of drug distribution, metabolism amd elimination;

    the mechanisms mediating the development of the adverse drug reactions and their toxic effects; the possible causes of hydiosyncratic and allergic reactions toward drugs, included principle of pharmacogenetics and of drug-drug interactions;

    the criteria to select different molecules within the same pharmacological class, referring to their potential toxicity and individual features of the patient.

    TEACHING METHODS

    Teaching of pharmacology will be performed by frontal lessons

    SYLLABUS/CONTENT

    1) Introduction to the pharmacology

     Drug development at preclinical levle and the clinical trials

    Pharmacognosy

    2) Drug administration routes

    Bioavailability

    Drug adsorption

    Distribution

    Drug metabolism and its modulation

    Drug excretion

    3) Drug activity: agonism antagonism

    Therapeutic index

    Tolerance

    4) Receptors and their functioning as mechanism of action of the drugs

    5) Adverse drug reactions and mechanisms inducing the individual differences in the drug activity

    6) Drug acting on the autonomic nervous system

    7) Local anesthetics

    8) NSAID

    9) Glucocorticoids

    10) Benzodiazepines

    11) Basics of antibacterial therapy

    12) Beta-lactamic antibiotics (penicillins, cephalosporins, etc)

    13) Glycopeptides

    14) Macrolides

    15) Fluorochinolones and other secnond choice antibiotics

    16) Aminoglucosides, tetracyclines, CAF

    17) Antifungines

    18) Antiviral drugs

    19) Antiplatelets, anticoagulats, antihaemerragic drugs

    20) Drugs affecting calcium metabolism

    21) Antihistaminergic drugs

    22) Drugs used in emergency

    23) Drug prescription rules

     

     

     

    RECOMMENDED READING/BIBLIOGRAPHY

    1) Amico-Roxas M., Caputi A., Del Tacca M., Farmacologia in Odontoiatria, UTET

    2) Katzung, Farmacologia, Piccin

    All the slides used during the lessons will be made available to the students through aulaweb

    TEACHERS AND EXAM BOARD

    Exam Board

    FEDERICA BARBIERI (President)

    TULLIO FLORIO (President)

    LESSONS

    LESSONS START

    II semester

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    The exam of pharmacology will be performed as an interview

    ASSESSMENT METHODS

    The interview will evaluate the knowledge of the student about the mechanisms regulating the interactions between drugs and human body, the mechanism of action, the clinical use and the sire effects of the drugs used during the odontoiatric practoce, and the possible interferences between these pharmacologcal clases and the drugs of common use in the general population

    Exam schedule

    Date Time Location Type Notes
    11/01/2022 09:00 GENOVA Orale esame in presenza presso ex-Istituto di Farmacologia (viale benedetto XV, salvo indicazioni dell'Autorità Saniaria e/o Accademica
    24/01/2022 14:00 GENOVA Orale esame in presenza presso ex-Istituto di Farmacologia (viale benedetto XV, salvo indicazioni dell'Autorità Saniaria e/o Accademica
    25/02/2022 09:00 GENOVA Orale esame in presenza presso ex-Istituto di Farmacologia (viale benedetto XV, salvo indicazioni dell'Autorità Saniaria e/o Accademica
    27/06/2022 09:00 GENOVA Orale Esami presso l'aula di Farmacologia, viale Benedetto XV, num 4
    11/07/2022 09:00 GENOVA Orale Esami presso l'aula di Farmacologia, viale Benedetto XV, num 4
    25/07/2022 09:00 GENOVA Orale esame presso l'aula di Farmacologia viale Benedetto XV num 4
    25/07/2022 09:00 GENOVA Orale esame presso l'aula di Farmacologia vial Benedetto XV num 4
    27/09/2022 09:00 GENOVA Orale Esami presso l'aula di Farmacologia, viale Benedetto XV, num 4