CODE 34001 ACADEMIC YEAR 2016/2017 CREDITS 4 cfu anno 3 CHIMICA E TECNOLOGIE CHIMICHE 8757 (L-27) - SCIENTIFIC DISCIPLINARY SECTOR CHIM/06 LANGUAGE Italiano TEACHING LOCATION SEMESTER 2° Semester PREREQUISITES Propedeuticità in ingresso Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami: Chemistry and Chemical Technologies 8757 (coorte 2014/2015) ORGANIC CHEMISTRY 2 65109 2014 MATHEMATICAL INSTITUTIONS 72564 2014 AIMS AND CONTENT LEARNING OUTCOMES To give a general idea of various aspects where organic chemistry is connected with biology. In particular: functioning of proteins, use of them in organic synthesis and interaction of proteins with potential drugs. TEACHING METHODS Traditional lessons in the classroom (32 hours). The attendance is not compulsory but, for statistical means, it wil be anyway monitored. SYLLABUS/CONTENT Protein: secondary, tertiary and quaternary structure Enzymes: kynetics, catalysis mechanism, examples, classification . Principle of drug discovery. Enzyme inhibitors, receptors, ion channels. Glycochemistry. Applications in the fields of antiviral, antitumor drugs, antibiotics, antiinflammatory drugs, anti-asthma drugs, drugs for cardiovascular diseases and so on. RECOMMENDED READING/BIBLIOGRAPHY Silverman, R.B., "The Organic Chemistry of Drug Design and Drug Action", Academic Press Corey, E.J., Czakó, B. Kürti, L., "Molecules and Medicines", Wiley TEACHERS AND EXAM BOARD LUCA BANFI Ricevimento: Luca Banfi is always present in the department from 8.30 to 13.00 and from 15.00 to 18.30. However, due to the many lessons and exams he is involved in and to the institutional meetings, it is impossible to establish in advance a time interval where he will be surely not engaged. Therefore students are pleased to take an appointment in advance by E-mail. They will be received in few days. Exam Board LUCA BANFI (President) ANDREA BASSO (President) RENATA RIVA LESSONS LESSONS START From february, 20, 2017 (according to the timetable that will be reported on http://www.chimica.unige.it/it/didattica/orari_CTC). Class schedule BIOORGANIC CHEMISTRY EXAMS EXAM DESCRIPTION The exam will be oral. Only the subjects treated during the lessons (as reported in the slides deposited in aulaweb) will be object of the exam. Students must register to the exam at least 48 hours in advance on https://servizionline.unige.it/studenti/esami/prenotazione ASSESSMENT METHODS The oral exam is always carried out by two teachers with at least 5 years of experience and will last at least 30 minutes. In this way, the commission is definitely able to verify with high accuracy if the student has reached or not the learning outcomes. During the oral exam the student must demonstrate to have reached the learning outcomes, both orally and (most importantly) writing formulas, chemical equations, mechanisms. When the commission will judge that the learning oucomes have not been reached, the students willbe invited to repeat the exam in one of the subsequent dates. Exam schedule Data appello Orario Luogo Degree type Note 24/05/2017 15:00 GENOVA Orale 08/06/2017 09:00 GENOVA Orale 21/06/2017 15:00 GENOVA Orale 19/07/2017 09:00 GENOVA Orale 18/09/2017 09:00 GENOVA Orale 11/10/2017 15:00 GENOVA Orale 25/10/2017 15:00 GENOVA Orale 15/11/2017 09:00 GENOVA Orale FURTHER INFORMATION The exam must be preceded by: Organic Chemistry 2 Laboratory of Organic Chemistry Institutions of Mathematic
