CODE 67617 ACADEMIC YEAR 2016/2017 CREDITS 8 cfu anno 5 CHIMICA E TECNOLOGIA FARMACEUTICHE 8451 (LM-13) - SCIENTIFIC DISCIPLINARY SECTOR CHIM/09 LANGUAGE Italiano TEACHING LOCATION SEMESTER 1° Semester PREREQUISITES Propedeuticità in ingresso Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami: Pharmaceutical chemistry and technology 8451 (coorte 2012/2013) ORGANIC CHEMISTRY II (PCT)(MD) 60828 2012 PHARMACEUTICAL TECHNOLOGY AND LAW I (PCT MD) 67569 2012 OVERVIEW Applied Medicinal Chemistry is the discipline dealing with all the technological, scientific and bureaucratic aspects indispensable in order to develop and launch on the pharmaceutical market a new drug. Therefore in this course all the strategies carried out by pharmaceutical companies to optimize safety and bioavailability of the new active ingredient are exhaustively treated. AIMS AND CONTENT LEARNING OUTCOMES Providing students all the fundamental principles they need to join a team of researchers of pharmaceutical companies involved in the design and development of a new drug endowed with high therapeutic index. LEARNING OUTCOMES (FURTHER INFO) Providing students all the fundamental principles about drug discovery and development, INN and IUPAC nomenclature of organic drugs, preformulation and biopharmaceutics studies, drugs metabolism, drugs targeting and advances in pharmaceutical polymers. TEACHING METHODS Theoretical lessons are aimed at simplifying the comprehension of the pharmaceutical topics treated. In this context the teacher supports particular closer examination of aspects particularly difficult to understand for students. Before starting a new lesson, to facilitate students to learn several connected chapters, a brief summing up of the previous lesson is carried out. SYLLABUS/CONTENT Drug Discovery and development INN and IUPAC nomenclature of organic drugs The development of new active ingredients Preformulation studies Biopharmaceutics Drugs metabolism Drugs targeting Macromolecules and pharmaceutics RECOMMENDED READING/BIBLIOGRAPHY A particular book to make reference to Applied Medicinal Chemistry doesn't exist. The 9 chapters of the course are composed by topics put together properly by the teacher and deriving from updated and reliable reviews in the field of medicinal chemistry. Each chapter is exaustively explained to students throughout the lessons and for every chapter comprehensive notes are available on Aulaweb. TEACHERS AND EXAM BOARD GIANCARLO GROSSI Ricevimento: Depending on his own professional engagements and by appointment, the teacher is always available to receive students. Exam Board GIANCARLO GROSSI (President) ELEONORA RUSSO CARLA VILLA LESSONS LESSONS START Classes usually start every year around the 20th of September with a weekly engagement of 6 hours splitted among three lessons each lasting two hours. Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The Applied Medicinal Chemistry exam is divided into two parts: the first one about drugs IUPAC nomenclature is written and carried out during the course; the second one is oral and lasts about 45 minutes for each students. Questions deal with 5 topics chosen by the teacher among the subjects treated during the course. ASSESSMENT METHODS Since Applied Medicinal Chemistry Course deals with topics about the chemistry and bioavailability of most successful drugs, teacher assesses student's ability to both explain clearly and write correctly chemical structures involved in the exam questions. Exam schedule Data appello Orario Luogo Degree type Note 14/04/2017 09:00 GENOVA Orale 14/06/2017 09:00 GENOVA Orale 07/07/2017 09:00 GENOVA Orale 24/07/2017 09:00 GENOVA Orale 13/09/2017 09:00 GENOVA Orale 24/01/2018 14:00 GENOVA Orale 14/02/2018 14:00 GENOVA Orale FURTHER INFORMATION Throughout the course but also before exams, depending on student's request, the teacher is available to offer additional explanations about subjects discussed during the course and considered more difficult to learn by students.
