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CODE 80830
ACADEMIC YEAR 2016/2017
CREDITS
SCIENTIFIC DISCIPLINARY SECTOR BIO/10
LANGUAGE Italiano
TEACHING LOCATION
SEMESTER 2° Semester
TEACHING MATERIALS AULAWEB

AIMS AND CONTENT

LEARNING OUTCOMES

The aim of the course is to provide students with theoretical knowledge but also practical on the assumptions and techniques underlying the engineering of proteins and antibodies. In addition, part of the course will be dedicated to the deepening of the techniques of chemical synthesis of proteins.

Regarding the form of Protein engineering, will initially be resumed and expanded some concettivi base relative to the production of recombinant proteins. Thus, different approaches will be analyzed in order to obtain modified proteins or optimized for different applications, the techniques used and the systems of selection / screening, and using examples from the literature or used for production / commercial.

In the section of the course on the engineering of antibodies will be given with the three-dimensional structure of immunoglobulins and will be addressed later, in the chronological order of creation, the different techniques of humanization and production of recombinant phage display antibody.

In the form of Chemical Engineering explain the main techniques for the chemical synthesis of peptides and proteins and applications resulting from these techniques.

TEACHING METHODS

Frontal lessons.

RECOMMENDED READING/BIBLIOGRAPHY

There are currently no adequate texts. In addition to lecture notes, students will have the educational materials in the form of handouts and publications from the scientific literature.

TEACHERS AND EXAM BOARD

Exam Board

MICHELA TONETTI (President)

FABIO GIUSEPPE GHIOTTO

ENRICO MILLO

LESSONS

LESSONS START

March 1, 2017.

Class schedule

PROTEIN ENGINEERING

EXAMS

EXAM DESCRIPTION

Oral.

ASSESSMENT METHODS

The assessment of the achievement of educational objectives will be effected by oral exams. The date of the appeals will be agreed with the students.