CODE 68476 ACADEMIC YEAR 2016/2017 CREDITS 1 cfu anno 2 TECNICHE DI LABORATORIO BIOMEDICO (L/SNT3) - SCIENTIFIC DISCIPLINARY SECTOR BIO/10 LANGUAGE Italiano TEACHING LOCATION SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: CLINICAL BIOCHEMISTRY AND CLINICAL CHEMISTRY TECHNIQUES TEACHING MATERIALS AULAWEB AIMS AND CONTENT LEARNING OUTCOMES Human systematic biochemistry describes how cells extract energy from fuel molecules like fatty acids and carbohydrates, how the body controls the rate of fuel utilisation and how the mix of fuels is regulated under different physiological circumstances such as starvation and exercise. The metabolic inter-relationships of the liver, muscle, adipose tissue and brain and the role of hormones in coordinating tissue metabolic relationships is discussed. TEACHING METHODS Teaching is performed by classroom-taught lessons with the aid of slides that are available to the students on the Aulaweb SYLLABUS/CONTENT Human Systematic Biochemistry: main metabolic pathways - mechanisms for the regulation of the metabolism of charboydrates, lipids and proteins.Metabolism integration and cell metabolic specialization. Liver: cellular organization and functions- specific metabolisms and their regulation (glycolisis and gluconeogenesis, glycogen; synthesis of different lipids, cholesterol, lipoproteins, aminoacids and urea cycle) - relationship between the liver and other organs. Muscle: molecular bases of muscle contraction-specific metabolisms and their regulation-metabolic relationships with other tissues. Adipose tissue: structure and function- specific imetabolisms and their regulation: signals for lipid mobilization-heat production. Intestinal metabolism: digestion of charboydrates, lipids, proteins,vitamins and nucleic acids. Central nervous system: specific metabolisms and their regulation, syntesis of neurotransmitters. Blood: composition and role in the transport of metabolites- glycemia - transport of O2 e CO2 - ionic equilibrium, plasma proteins and lipids transport. Hormonal control: main classes of hormones and their functions- hormon regulation of the energetic metabolism- metaboliche changes following fasting and physical exercise. RECOMMENDED READING/BIBLIOGRAPHY Denise R. Ferrier: Le basi della biochimica - Editore: Zanichelli TEACHERS AND EXAM BOARD MARIO PASSALACQUA Ricevimento: On appointment Prof. Mario Passalacqua, Via L.B. Alberti 2 -16132 Genova Tel 010-3538835 e-mail: Mario.Passalacqua@unige.it Exam Board BIANCA SPARATORE (President) MICHELE BAROFFIO ELISABETTA FRATERNALE LAURA MARCOMINI MARIO PASSALACQUA LESSONS Class schedule HUMAN BIOCHEMISTRY EXAMS Exam schedule Data appello Orario Luogo Degree type Note 12/06/2017 14:00 GENOVA Orale 03/07/2017 14:00 GENOVA Orale 18/09/2017 14:00 GENOVA Orale