Human systematic biochemistry describes how cells extract energy from fuel molecules like fatty acids and carbohydrates, how the body controls the rate of fuel utilisation and how the mix of fuels is regulated under different physiological circumstances such as starvation and exercise. The metabolic inter-relationships of the liver, muscle, adipose tissue and brain and the role of hormones in coordinating tissue metabolic relationships is discussed.
Teaching is performed by classroom-taught lessons with the aid of slides that are available to the students on the Aulaweb
Human Systematic Biochemistry: main metabolic pathways - mechanisms for the regulation of the metabolism of charboydrates, lipids and proteins.Metabolism integration and cell metabolic specialization. Liver: cellular organization and functions- specific metabolisms and their regulation (glycolisis and gluconeogenesis, glycogen; synthesis of different lipids, cholesterol, lipoproteins, aminoacids and urea cycle) - relationship between the liver and other organs. Muscle: molecular bases of muscle contraction-specific metabolisms and their regulation-metabolic relationships with other tissues. Adipose tissue: structure and function- specific imetabolisms and their regulation: signals for lipid mobilization-heat production. Intestinal metabolism: digestion of charboydrates, lipids, proteins,vitamins and nucleic acids. Central nervous system: specific metabolisms and their regulation, syntesis of neurotransmitters. Blood: composition and role in the transport of metabolites- glycemia - transport of O2 e CO2 - ionic equilibrium, plasma proteins and lipids transport. Hormonal control: main classes of hormones and their functions- hormon regulation of the energetic metabolism- metaboliche changes following fasting and physical exercise.
Denise R. Ferrier: Le basi della biochimica - Editore: Zanichelli
Ricevimento: On appointment Prof. Mario Passalacqua, Via L.B. Alberti 2 -16132 Genova Tel 010-3538835 e-mail: Mario.Passalacqua@unige.it
BIANCA SPARATORE (President)
MICHELE BAROFFIO
ELISABETTA FRATERNALE
LAURA MARCOMINI
MARIO PASSALACQUA
HUMAN BIOCHEMISTRY
