The Clinical Pathology III course deals with biological assays andlaboratory blood tests characteristic of organ and bone marrow transplantation and autoimmune diseases.
Aim of the course is to provide the principles underlie to a) organ and hematopoietic stem cell transplantation, b) main features of autoimmune diseases. This aim focusing on in vitro assays to evaluate donor-recipient compatibility and biological parameters indicating: graft rejection and GVHD, the presence and progression of autoimmune disease.
Classroom-taught lectures, queries and replies on the next lesson, problem-based learning
Organ and bone marrow transplantation, markers of transplant rejection, graft versus host disease (GVHD), methods to assess donor-recipient compatibility, methods to assess biological parameters during graft rejection and GVHD, basic principle of auto-reactivity, autoimmunity and autoimmune diseases, organ specific autoimmune diseases, autoimmune hepatitis, systemic autoimmune diseases, systemic lupus erythematosus, methods to assess biological parameters and diagnose autoimmune diseases.
Lectures notes will be made available to all students via Aulaweb. Some topic can be further analyzed on the following text references: Roitt's Essential Immunology, 13th Edition di Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt ; ISBN: 978-1-118-41577-1, 576 pages, January 2017, Wiley-Blackwell; and on the site: http://www.roitt.com/; Janeway’s Immunobiology Edition: 9th Author(s): Kenneth Murphy, Casey Weaver, Garland Science editor ISBN:9780815345053 Publication Date: March 28, 2016 Content Details: 904 pages | 621 illustrations, Language: English.
Ricevimento: Students can book an appointment with the professor usually by e-mail;professor and students will agree on date and time. Alessandro Poggi MSc, MD, Molecular Oncology and Angiogenesis Unit,CBA/IST North tower C4,IRCCS AOU San Martino IST Largo R. Benzi 10,16132 Genoa, Italy, Phone.+39-0105558433, Fax: +39-010354282
ALESSANDRO POGGI (President)
OTTAVIA BARBIERI
paolo CARLIER
NICOLA TRAVERSO (President and Coordinator of Integrated Course)
march 2017
CLINICAL PATHOLOGY III
Oral examination
The student will be examined answering three queries on procedures and biological parameters relevant in pathological/clinical conditions that are subject of the course. The examination will be passed if the student knows and is able to assess which biological parameters should be studied in those pathological/clinical conditions.
