The course aims at providing students with the basic knowledge of the morphological and functional characteristics of human tissues with special regard to cells composing them. The course will also deal with the fundamental processes of embryonic development. Tutorials devoted to observation of histological preparations by optical microscope will deepen the aspects discussed in the lessons.
Knowledge of the main morphological and functional characteristics of human tissues with special regard to cells composing them. Skills in observation and recognition of tissues by the common microscopic observation techniques. Knowledge of the fundamental processes of embryonic development and the major molecular mechanisms that regulate them.
The course includes classroom teaching lessons on topics of histology and embryology as well as tutorials devoted to the observation of histological preparations by optical microscope and by monitors connected with optical microscopes.
HISTOLOGY
Epithelial tissue:
Main characteristics of epithelia
Lining epithelia: organization and classification
Structural surface differentiations of epithelial cells (microvilli, stereocilia, cilia)
Secretory epithelia:
• exocrine glands
• endocrine glands
Sensorial epithelia.
Specialized epithelia.
Connective tissue:
Extracellular matrix:
• fibers
• ground substance
Cell components of connective tissue
Connective tissue proper
Support connective tissue: cartilage and bone tissue
Ossification
Trophic connective tissue: blood and lymph
Lymphatic tissue
Cells of the innate and adaptive immune system
Muscle tissue:
Myofibril structure and muscle contraction
Nerve tissue:
EMBRYOLOGY
Gametogenesis:
- Spermatogenesis and mechanisms of hormonal control
- Oogenesis and mechanisms of hormonal control; ovarian cycle; uterine cycle.
Fertilization
Segmentation
Implantation of the blastocyst
Germ disc bilaminar (second week of development)
Germ disc trilaminar (third week of development)
Neurulation, the development of the somites and the embryonic body cavity, the embryo folding steps
The derivatives of the three germ layers.
Primitive placenta
Terminal placenta: leafy chorion and decidua
Amnion and umbilical cord.
Maternal-fetal compatibility/incompatibility.
Elements of organogenesis.
HISTOLOGY:
Young, Heath- Atlante: Istologia e Anatomia microscopica. Casa Editrice Ambrosiana
Ross M.H., Pawlina W.- Istologia- Testo e Atlante. Casa Editrice Ambrosiana
Maraldi, Tacchetti - Istologia medica - Edi-Ermes
Monesi – Istologia. Piccin Editore
EMBRYOLOGY:
Rosati e coll.- Embriologia. Edi-Ermes
De Felici e coll.- Embriologia umana. Piccin Editore
http://www.istologia.unige.it/
Ricevimento: By appointment by email: alemoret@unige.it
Ricevimento: By appointment by email: antonio.puccetti@unige.it
Ricevimento: By appointment by email: roberta.castriconi@unige.it
Ricevimento: By appointment by e-mail: emanuela.marcenaro@unige.it
Ricevimento: By appointment by email: simona.sivori@unige.it
ROBERTA CASTRICONI (President)
EMANUELA MARCENARO (President)
ALESSANDRO MORETTA (President)
ANTONIO PUCCETTI (President)
SIMONA SIVORI (President)
Oral examination.
The examination includes two tests. The first consists of a practical test where the student must describe two histological preparations by the use of optical microscope. The second test, performing only upon the positive evaluation of the first test, consists of an oral examination by two different holders of the course. The examamination has a duration of at least 30 minutes (typically 45 minutes).
