CODE 58031 ACADEMIC YEAR 2017/2018 CREDITS 10 cfu anno 1 MEDICINA E CHIRURGIA 8745 (LM-41) - SCIENTIFIC DISCIPLINARY SECTOR BIO/10 LANGUAGE Italian TEACHING LOCATION SEMESTER 2° Semester PREREQUISITES Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: MEDICINE AND SURGERY 8745 (coorte 2017/2018) HUMAN PHYSIOLOGY 61191 MODULES Questo insegnamento è un modulo di: BIOCHEMISTRY OVERVIEW Biochemistry, together with molecular biology and human genetics, is necessary to understand the molecular events underlying human physiology and pathology. This Course will teach the basic mechanisms of chemical and metabolic modifications in order to understand the molecular basis of diseases. AIMS AND CONTENT AIMS AND LEARNING OUTCOMES At the end of this course, the student must have acquired an understanding of the biochemical reactions of the major anabolic and catabolic pathways, and of their relevance to understand the molecular basis of disease. TEACHING METHODS Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together. SYLLABUS/CONTENT Proteins: composition and structure (Teacher Prof. Franca Salamino) Proteins:structure-function relationships in protein families (Teacher Prof. Franca Salamino) Enzymes: classification kinetics and control (Teacher Prof. Franca Salamino) Bioenergetics and oxidative metabolism (Teacher Prof. Franca Salamino) Carbohydrate metabolism: major metabolism and their control (Teacher Prof. Michela Tonetti) Carbohydrate metabolism: special pathways (Teacher Prof. Michela Tonetti) Lipid metabolism: transport, utilization and storage of energy in lipid form (Teacher Prof. Franca Salamino) Lipid metabolism: pathways of metabolism of special lipids (Teacher Prof. Franca Salamino) Aminoacid metabolism (Teacher Prof. Elena Zocchi) Purine and pyrimidine nucleotide metabolism: metabolic interrelationships (Teacher Prof. Elena Zocchi) Biochemistry of hormones: polypeptide hormones(Teacher Prof. Elena Zocchi) Biochemistry of hormones: steroid hormones (Teacher Prof. Elena Zocchi) Iron and heme metabolism (Teacher Prof. Franca Salamino) Principle of nutrition: water soluble vitamins and lipid soluble vitamin(Teacher Prof. Michela Tonetti) RECOMMENDED READING/BIBLIOGRAPHY Materials published in Aula Web Texbook: Nelson and Cox: Lehninger Principles of Biochemistry w.h. freeman ed. Devlin: Textbook of biochemistry with clinical correlations Wiley-Liss ed TEACHERS AND EXAM BOARD SANTINA BRUZZONE Ricevimento: By appointment by email: santina.bruzzone@unige.it Office: DIMES, Section of Biochemistry, Viale Benedetto XV, 1 (Genova) Phone: 0103538161 MICHELA TONETTI Ricevimento: The teacher receives by appointment at Biochemistry - DIMES, Viale Benedetto XV No. 1, first floor, Genoa. The talks may take place, by appointment, also via Skype For appointments please send an email to: tonetti@unige.it. ELENA ZOCCHI Ricevimento: upon appointment by e-mail Exam Board SANTINA BRUZZONE (President) GIANLUCA DAMONTE (President) MICHELA TONETTI ELENA ZOCCHI (President and Coordinator of Integrated Course) LESSONS LESSONS START 6 march 2017 Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral exam. Students should pass the Biochemistry 1 test before enlisting for the Biochemistry 2 oral exam. The final score will include both subjects. ASSESSMENT METHODS The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes. Exam evaluation will take into account knowledge, presentation/speaking skills, as well as the ability in connecting the different arguments. Exam schedule Data appello Orario Luogo Degree type Note 16/01/2018 09:30 GENOVA Orale 16/01/2018 09:30 GENOVA Orale 02/02/2018 15:00 GENOVA Scritto + Orale 16/02/2018 15:00 GENOVA Scritto + Orale 20/02/2018 09:30 GENOVA Orale 20/02/2018 09:30 GENOVA Orale 16/03/2018 14:00 GENOVA Scritto + Orale 15/06/2018 15:00 GENOVA Scritto + Orale 19/06/2018 09:30 GENOVA Orale 19/06/2018 09:30 GENOVA Orale 29/06/2018 15:00 GENOVA Scritto + Orale 10/07/2018 09:30 GENOVA Orale 10/07/2018 09:30 GENOVA Orale 20/07/2018 15:00 GENOVA Scritto + Orale 25/07/2018 09:30 GENOVA Orale 25/07/2018 09:30 GENOVA Orale 11/09/2018 09:30 GENOVA Orale 11/09/2018 09:30 GENOVA Orale 21/09/2018 15:00 GENOVA Scritto + Orale 26/09/2018 09:30 GENOVA Orale 26/09/2018 09:30 GENOVA Orale
