OVERVIEW

Neuropharmacology is the science that study the drugs active on the CNS. This include the study of the origin and the chemical structure of the drugs, the molecular mechanisms the mediate their effects inthe the body, the pharmacokinetics, their clinical use, their toxicity, and the adverse reactions that they can determine.

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

At the end of the course the student should know the molecular mechanisms of action of the main classes of CNS drugs, focusing on their modulatory effects on the specifi neurotransmitter systems whose activity is altered in neuropschyatric diseases. Furthermore the side effects caused by the drug specific modulation of the main neurotransmitter system or by effects on other pathways should be known.

TEACHING METHODS

Frontal teaching

SYLLABUS/CONTENT

1) Pharmacological control of pain: opiates

2) Dopaminergic agonists in the treatment of Parkinson disease and antagonists for the treatemtn of schizofrenia

3) Serotonin and noradrenaline uptake inhibitors in the treatment of depression

4) GABA receptor agonosts as anxiolytic drugs

5) Activation of cholinergic system for AD treatment

6) Ion current modulation as pharmacological targets to treat epilepsy

7) Pharmacology of the cannabinoid system

RECOMMENDED READING/BIBLIOGRAPHY

Slides of all the lessons will be provided throughg AULAWEB.

TEACHERS AND EXAM BOARD

Exam Board

TULLIO FLORIO (President)

GIOVANNI LUIGI MANCARDI (President)

GIOVANNI ABBRUZZESE

STEFANO THELLUNG DE COURTELARY

ANTONIO UCCELLI

LESSONS

LESSONS START

II semester

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

Oral examination

ASSESSMENT METHODS

Discussion of the main issues discussed during the lessons

Exam schedule