Comprehensive analysis of stem cell biology, with specific focus on their differentiation and therapeutic potential (including somatic nuclear transfer and cloning).
Frontal lessons and laboratory.
Stem cells: stemness characterisation and historical background.
Embryonic – Fetal – Adult Stem Cells. Stem versus Differentiation Potential.
The Stem Cell Niche. Stem Cell Pluripotency and Plasticity. Stem Cell Markers and “Stem Genes”.
Adult Stem Cells: Haematopoietic-, Epithelial-, Neural- and Mesenchymal Stem Cells.
Somatic Nuclear Transfer in amphibians and mammals. Cloning.
Fetal and Perinatal Stem Cells
EMT in Cell Biology: Epithelial - Mesenchymal Transition
Tissue-Specific Adult Progenitors within the Heart.
Epicardial Progenitor Cells (EPDC): Proof-of-Principle of EMT in Cardiac Development and Regeneration.
Tissue-Specific Adult Progenitors within the Skeletal Muscle.
Stem Cells, DNA damage & Ageing.
Stem Cells & miRNA
Inter-Cellular Communication 2.0: Extracellular Microvesicles
De-Differentiation, Trans-Differentiation and Reprogramming.
Journal Club: Oral presentation from groups of students on specific articles from the topic discussed during class.
Hands On Practice on Cell Culture Laboratory
Ricevimento: By appointment by email: sveva.bollini@unige.it
Ricevimento: By appointment by email: ranieri.cancedda@unige.it
SVEVA BOLLINI (President)
CHIARA GENTILI (President)
RANIERI CANCEDDA
October 1, 2017
CELL BIOLOGY II AND LABORATORY COURSE
Written
Written test
