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CODE 95302
ACADEMIC YEAR 2017/2018
CREDITS
SCIENTIFIC DISCIPLINARY SECTOR BIO/13
LANGUAGE English
TEACHING LOCATION
SEMESTER 1° Semester
PREREQUISITES
Propedeuticità in uscita
Questo insegnamento è propedeutico per gli insegnamenti:
  • MEDICAL-PHARMACEUTICAL BIOTECHNOLOGY 10598 (coorte 2017/2018)
  • MOLECULAR BIOLOGY 2 AND LABORATORY 95300
TEACHING MATERIALS AULAWEB

AIMS AND CONTENT

LEARNING OUTCOMES

Comprehensive analysis of stem cell biology, with specific focus on their differentiation and therapeutic potential (including somatic nuclear transfer and cloning).

TEACHING METHODS

Frontal lessons and laboratory.

SYLLABUS/CONTENT

Stem cells: stemness characterisation and historical background.

Embryonic – Fetal – Adult Stem Cells. Stem versus Differentiation Potential.

The Stem Cell Niche. Stem Cell Pluripotency and Plasticity. Stem Cell Markers and “Stem Genes”.

Adult Stem Cells: Haematopoietic-, Epithelial-, Neural- and Mesenchymal Stem Cells.

Somatic Nuclear Transfer in amphibians and mammals. Cloning.

Fetal and Perinatal Stem Cells

EMT in Cell Biology: Epithelial - Mesenchymal Transition

Tissue-Specific Adult Progenitors within the Heart.

Epicardial Progenitor Cells (EPDC): Proof-of-Principle of EMT in Cardiac Development and Regeneration.

Tissue-Specific Adult Progenitors within the Skeletal Muscle.

Stem Cells, DNA damage & Ageing.

Stem Cells & miRNA

Inter-Cellular Communication 2.0: Extracellular Microvesicles

De-Differentiation, Trans-Differentiation and Reprogramming.

 

Journal Club: Oral presentation from groups of students on specific articles from the topic discussed during class.

 

Hands On Practice on Cell Culture Laboratory

TEACHERS AND EXAM BOARD

Exam Board

SVEVA BOLLINI (President)

CHIARA GENTILI (President)

RANIERI CANCEDDA

LESSONS

LESSONS START

October 1, 2017

EXAMS

EXAM DESCRIPTION

Written

ASSESSMENT METHODS

Written test

Exam schedule

Data appello Orario Luogo Degree type Note
16/01/2018 14:00 GENOVA Orale
13/02/2018 14:00 GENOVA Orale
18/06/2018 14:00 GENOVA Orale
16/07/2018 14:00 GENOVA Orale
17/09/2018 14:00 GENOVA Orale