OVERVIEW

The course of Molecular Pathology deals with the study of specific molecular alterations which lead to disease.

AIMS AND CONTENT

LEARNING OUTCOMES

In-depth knowledge about inheritance as it occurs in human beings, and comprehension of the main molecular and cellular mechanisms related to the pathogenesis of inherited and acquired diseases.

AIMS AND LEARNING OUTCOMES

The course aims to provide students with the fundamental elements about the pathways through which molecular alterations, either inherited or acquired, can lead to disease.

TEACHING METHODS

The course is organized in frontal lessons. The topics included in the syllabus will be explained by the professor through PowerPoint presentations. Students will be triggered to ask questions and formulate answers in interactive modality. During the course lessons may be organized where students will be encouraged to discuss with the professor scientific papers related to the syllabus.

SYLLABUS/CONTENT

Molecular pathology of carbohydrates: pathogenesis and complications of diabetes mellitus.

Molecular pathology of lipids: alterations of lipoprotein metabolism.

Molecular pathology of aminoacids: phenylketonuria.

Molecular pathology of blood cells and of the immune system:

1) Genetic defects of innate immunity.

2) Autoinflammatory disorders.

3) Genetic defects leading to autoimmune disorders.

4) Genetic defects of erythrocytes.

5) Genetic defects of platelets and coagulation.

RECOMMENDED READING/BIBLIOGRAPHY

Lecture notes and reviews covering the whole course will be available for the students in Aulaweb.

TEACHERS AND EXAM BOARD

Exam Board

CLAUDIA CANTONI (President)

ISABELLA CECCHERINI (President)

NICOLA TRAVERSO (President)

LESSONS

LESSONS START

March 1, 2018

Class schedule

MOLECULAR PATHOLOGY AND LABORATORY

EXAMS

EXAM DESCRIPTION

The exam consists of an oral test and takes place in the presence of the two professors.

ASSESSMENT METHODS

Each student will be examined about the contents of at least two topics of the subject, with questions apt to evaluate his/her knowledge and ability of connecting different parts of the course. The knowledge and the definition of the basic elements of the subject are necessary for the achievement of the test. When the educational objectives of teaching are not met, the student is invited to deepen the study and to ask the professors for further clarification.

Exam schedule