CODE 61770 ACADEMIC YEAR 2017/2018 CREDITS 2 cfu anno 2 BIOLOGIA MOLECOLARE E SANITARIA 9015 (LM-6) - SCIENTIFIC DISCIPLINARY SECTOR BIO/09 LANGUAGE Italian TEACHING LOCATION SEMESTER 1° Semester AIMS AND CONTENT LEARNING OUTCOMES Provide students with an adequate insight into the substances present in the environment and how these can interfere with the proper functioning of natural hormones in humans TEACHING METHODS lesson SYLLABUS/CONTENT Endocrine disrupting chemicals (EDCs): Definition and Background. Biomagnification Bioaccumulation and LOEL. Molecular EDC Mechanisms. Assays for identifying EDCs. EDCs and ovarian function: polycystic ovary syndrome, endometriosis. Leiomioma / Fibroma, premature puberty, decreased fertility and pregnancy probability, premature birth, underweight birth, menstrual cycle alteration. EDCs and male reproductive health: congenital cryptorchidism, hypospadia, seed quality, testicular dysgeesis syndrome, testicular germ cell carcinoma. EDCs and thyroid hormones: thyroid or thyroid nodules, Congenital hypothyroidism, Thyroiditis autoimmune, Hyperthyroidism or Graves' disease, Thyroid cancer. EDCs and cancer: hormone tumors Of the breast, endometrial, Of the ovaries, Of the testicles, Of the prostate and Of the thyroid. EDCs and alterations of lipid homeostasis. RECOMMENDED READING/BIBLIOGRAPHY Slides and material provided by the teacher TEACHERS AND EXAM BOARD ELENA GRASSELLI Ricevimento: On appointment Exam Board ELENA GRASSELLI (President) LAURA CANESI ILARIA DEMORI ADRIANA VOCI LESSONS LESSONS START To agree with the students Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral Exam schedule Data appello Orario Luogo Degree type Note 24/01/2018 10:00 GENOVA Orale 13/02/2018 14:30 GENOVA Orale 12/06/2018 14:30 GENOVA Orale 26/06/2018 14:30 GENOVA Orale 10/07/2018 14:30 GENOVA Orale 18/09/2018 14:30 GENOVA Orale