AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course aims at providing students with basic knowledge on Clinical Biochemistry, the clinical diagnostic and prognostic significance of the common laboratory tests exploring organ and tissue funtion.

At the end of the course, students will know the principal clinical-biochemistry indicators of organ and tissue function and will be able to identify out-of-range parameters and apply an analytical reasoning to critically evaluate the clinical-chemistry profile in relationship to the working risks.

TEACHING METHODS

Plenary lectures will present the laboratory tests described in the programme, the normal range of the values and their dynamic excursion during common organ and tissue diseases.

A number of simple clinical cases will be presented to allow students to train the clinical reasoning on the basis of evidence provided by the clinical laboratory tests.

SYLLABUS/CONTENT

BLOOD
Blood cell count, electrophoretic profile of serum proteins and diagnostic value, common serum enzymes of diagnostic value, non-protein nitrogen, electrolytes.

LIVER FUNTION TESTS

Serum enzymes in the diagnosis of liver diseases, bilirubin and jaundice, laboratory tests in selected liver diseases (viral hepatitis, alcoholism, toxic liver diseases).

TEST EXPLORING GLUCOSE METABOLISM
Causes of yper- and hypo-glycemia, diagnostic criteria of diabetes mellitus, gestational diabetes

TESTS EXPLORING LIPID METABOLISM
Lipoprotein classification, dyslipidemic phenotypes, cardiovascula risk, laboratory diagnosis of AMI

URINEANALYSIS AND TESTS OF RENAL FUNCTION
Physical-chemical urine analysis, indicators of glomerular and tubular malfunction

ENDOCRINOLOGY
Steroid hormones, peptide hormones and hormonse derived from aminoacids: basal levels and conditions of hyper- and hypo-production. Lab tests exporing hormone blood and urine levels.

BLOOD GASES
Normal values and modifications in selected conditions

VITAMINS
Function in metabolism and principal diseases caused by deficiency.

RECOMMENDED READING/BIBLIOGRAPHY

slides by the teacher available online (aula-web)

TEACHERS AND EXAM BOARD

Exam Board

CECILIA TRUCCHI (President)

MARCO CAPPELLI

MONICA FORTIN

SEBASTIANO LA MAESTRA

ALESSANDRA RUBAGOTTI

ELENA ZOCCHI

DANIELA AMICIZIA (President and Coordinator of Integrated Course)

LESSONS

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

multiple-choice test

ASSESSMENT METHODS

A written exam (multiple-choice test) will verify acquisition of the knowledge relative to the topics dealt with during the course and the student's ability to critically evaluate precompiled answers, demonstrating independent reasoning. In particular, the "normal range" of the laboratory tests will be explored and their dynamic range under conditions of organ or tissue disease. Some questions will explore the capacity of the student to identify laboratory tests indicated to provide an answer in specific diagnostic settings.

Exam schedule