AIMS AND CONTENT

LEARNING OUTCOMES

To give a general idea of various aspects where organic chemistry is connected with biology. In  particular: structure functioning of proteins (enzymes, receptors, channels) and oligosaccharides, and their interaction with potential drugs.

TEACHING METHODS

Traditional lessons in the classroom (32 hours). The attendance is not compulsory but, for statistical means, it wil be anyway monitored.

SYLLABUS/CONTENT

Protein: secondary, tertiary and quaternary structure Enzymes: kynetics, catalysis mechanism, examples, classification . Principle of drug discovery. Enzyme inhibitors, receptors, ion channels. Glycochemistry. Applications in the fields of antiviral, antitumor drugs, antibiotics, antiinflammatory drugs, anti-asthma drugs, drugs for cardiovascular diseases and so on.

RECOMMENDED READING/BIBLIOGRAPHY

• Silverman, R.B., "The Organic Chemistry of Drug Design and Drug Action", Academic Press
• Corey, E.J., Czakó, B. Kürti, L., "Molecules and Medicines", Wiley

TEACHERS AND EXAM BOARD

Exam Board

LUCA BANFI (President)

RENATA RIVA

LISA MONI (President Substitute)

CHIARA LAMBRUSCHINI (Substitute)

LESSONS

LESSONS START

2 march 2020 (timetable on http://www.chimica.unige.it/didattica/orari_CTC  or https://corsi.unige.it/8757)

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The exam will be oral. Only the subjects treated during the lessons (as reported in the slides deposited in aulaweb) will be object of the exam. Students must register to the exam at least 48 hours in advance on https://servizionline.unige.it/studenti/esami/prenotazione

ASSESSMENT METHODS

The oral exam is always carried out by two teachers with at least 5 years of experience and will last at least 30 minutes. In this way, the commission is definitely able to verify with high accuracy if the student has reached or not the learning outcomes.

During the oral exam the student must demonstrate to have reached the learning outcomes, both orally and (most importantly) writing formulas, chemical equations, mechanisms.

When the commission will judge that the learning oucomes have not been reached, the students will be invited to repeat the exam in one of the subsequent dates.

Exam schedule