CODE 58031 ACADEMIC YEAR 2021/2022 CREDITS 10 cfu anno 1 MEDICINA E CHIRURGIA 8745 (LM-41) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/10 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester MODULES Questo insegnamento è un modulo di: BIOCHEMISTRY TEACHING MATERIALS AULAWEB OVERVIEW Biochemistry, together with molecular biology and human genetics, is necessary to understand the molecular events underlying human physiology and pathology. This Course will teach the basic mechanisms of chemical and metabolic modifications in order to understand the molecular basis of diseases. AIMS AND CONTENT AIMS AND LEARNING OUTCOMES At the end of this course, the student must have acquired an understanding of the biochemical reactions of the major anabolic and catabolic pathways, and of their relevance to understand the molecular basis of disease. TEACHING METHODS Lectures will cover the entire program of the course. Three different Professors (Salamino, Tonetti e Zocchi) will alternate during the course, covering different parts of the program, as indicated in sylabus/ content. At the end of the lessons, at least 4 hours will be devoted to question-time by the students with the three Professors together. SYLLABUS/CONTENT Proteins: composition and structure (Teacher Prof. Santina Bruzzone) Proteins:structure-function relationships in protein families (Teacher Prof. Santina Bruzzone) Enzymes: classification kinetics and control (Teacher Prof. Santina Bruzzone) Bioenergetics and oxidative metabolism (Teacher Prof. Santina Bruzzone) Carbohydrate metabolism: major metabolism and their control (Teacher Prof. Michela Tonetti) Carbohydrate metabolism: special pathways (Teacher Prof. Michela Tonetti) Lipid metabolism: transport, utilization and storage of energy in lipid form (Teacher Prof. Santina Bruzzone) Lipid metabolism: pathways of metabolism of special lipids (Teacher Prof. Santina Bruzzone) Aminoacid metabolism (Teacher Prof. Elena Zocchi) Purine and pyrimidine nucleotide metabolism: metabolic interrelationships (Teacher Prof. Elena Zocchi) Biochemistry of hormones: polypeptide hormones(Teacher Prof. Elena Zocchi) Biochemistry of hormones: steroid hormones (Teacher Prof. Elena Zocchi) Biochemistry of liver, muscle and adipose tissue (Teacher Prof. Elena Zocchi) Iron and heme metabolism (Teacher Prof. Santina Bruzzone) Principle of nutrition: water soluble vitamins and lipid soluble vitamin(Teacher Prof. Michela Tonetti) RECOMMENDED READING/BIBLIOGRAPHY Materials published in Aula Web Texbook: Nelson and Cox: Lehninger Principles of Biochemistry w.h. freeman ed. Devlin: Textbook of biochemistry with clinical correlations Wiley-Liss ed TEACHERS AND EXAM BOARD MICHELA TONETTI Ricevimento: The teacher receives by appointment at Biochemistry - DIMES, Viale Benedetto XV No. 1, first floor, Genoa. The talks may take place, by appointment, also via Skype For appointments please send an email to: tonetti@unige.it. SANTINA BRUZZONE Ricevimento: By appointment by email: santina.bruzzone@unige.it Office: DIMES, Section of Biochemistry, Viale Benedetto XV, 1 (Genova) Phone: 0103538161 Exam Board SANTINA BRUZZONE (President) GIANLUCA DAMONTE (President) MIRKO BENVENUTI MICHELA TONETTI ELENA ZOCCHI (President and Coordinator of Integrated Course) LESSONS LESSONS START 6 march 2017 Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral exam. Students should pass the Biochemistry 1 test before enlisting for the Biochemistry 2 oral exam. The final score will include both subjects. ASSESSMENT METHODS The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes. Exam evaluation will take into account knowledge, presentation/speaking skills, as well as the ability in connecting the different arguments. Exam schedule Data appello Orario Luogo Degree type Note 14/01/2022 14:00 GENOVA Scritto 17/01/2022 09:00 GENOVA Orale 27/01/2022 09:00 GENOVA Orale 27/01/2022 09:00 GENOVA Orale 04/02/2022 14:00 GENOVA Scritto 10/02/2022 09:00 GENOVA Orale 10/02/2022 09:00 GENOVA Orale 24/02/2022 09:00 GENOVA Orale 24/02/2022 09:00 GENOVA Orale 25/02/2022 14:00 GENOVA Scritto 03/06/2022 14:00 GENOVA Scritto 06/06/2022 09:00 GENOVA Orale 06/06/2022 09:00 GENOVA Orale 06/06/2022 09:00 GENOVA Orale 06/06/2022 09:00 GENOVA Orale 06/06/2022 09:00 GENOVA Orale 23/06/2022 14:00 GENOVA Scritto 27/06/2022 09:00 GENOVA Orale 27/06/2022 09:00 GENOVA Orale 27/06/2022 09:00 GENOVA Orale 27/06/2022 09:00 GENOVA Orale 27/06/2022 09:00 GENOVA Orale 08/07/2022 14:00 GENOVA Scritto 11/07/2022 09:00 GENOVA Orale 11/07/2022 09:00 GENOVA Orale 11/07/2022 09:00 GENOVA Orale 11/07/2022 09:00 GENOVA Orale 11/07/2022 09:00 GENOVA Orale 26/07/2022 09:00 GENOVA Orale 26/07/2022 09:00 GENOVA Orale 26/07/2022 09:00 GENOVA Orale 16/09/2022 14:00 GENOVA Scritto 19/09/2022 09:00 GENOVA Orale 19/09/2022 09:00 GENOVA Orale 19/09/2022 09:00 GENOVA Orale 19/09/2022 09:00 GENOVA Orale 19/09/2022 09:00 GENOVA Orale
