AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

Acquire knowledge about the main toxicological actions caused by acute or chronic exposure of some classes of xenobiotics. Acquire the basic notions of drug / toxic-kinetics. In particular, knowledge will be required: of the mechanisms that regulate the absorption of drugs and toxic substances, with particular regard to the pathways of absorption / intoxication; their distribution, metabolism and elimination. Know the main aspects of pharmacodynamics in particular the mechanisms of action with which drugs and xenobiotics act. Know the organ-specific toxicity of various compounds. Know the possible pharmacological treatments in case of acute or chronic poisoning by pesticides, some heavy metals and gases and vapors.

TEACHING METHODS

Frontal lessons

SYLLABUS/CONTENT

Drug/toxic-kinetic overview: Absorption - Distribution - Metabolism - Elimination

Outline of drug-toxic-dynamics - DL50 - Safety data sheets

Organ-specific toxicity

Toxicity of the main heavy metals

Toxicity of the main pesticides

Toxicity of gases, vapors and solvents

RECOMMENDED READING/BIBLIOGRAPHY

The didactic material used during the lessons will be made available to students

Recommended supplementary text: “Elementi di tossicologia”  Casarett & Doul Casa Editrice Ambrosiana

TEACHERS AND EXAM BOARD

Exam Board

FRANCESCO D'AGOSTINI (President)

ANDREA DE MARIA (President)

BARBARA MARENGO

LUIGI ROBBIANO

VINCENZO TROVATO

CINZIA MARIA DOMENICOTTI (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

As per the didactic calendar

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The exam takes place in oral form.

ASSESSMENT METHODS

The verification of the correct understanding of the topics covered takes place during the exam with questions aimed at verifying the ability to actively apply the knowledge acquired during the course through reasoning and synthesis.

Exam schedule