AIMS AND CONTENT

LEARNING OUTCOMES

Learning computational techniques for the modeling of biological neural networks and understanding the brain and its function through a variety of theoretical constructs and computer science analogies.

AIMS AND LEARNING OUTCOMES

The emphasis is on neural information processing at “network level” in developing quantitative models, as well as in formalizing new paradigms of computation and data representation.

TEACHING METHODS

Lectures and case-study discussion.

SYLLABUS/CONTENT

• Neuron models: i) Biophysical model of neurons: passive and Hodgkin and Huxley models; ii) Reduced neuron models: Integrate-and-fire (IF) and Izhikevich models
• Synaptic transmission and plasticity: i) Phenomenological models; ii) Dynamical models; iii) Spike Timing Dependent Plasticity (STDP).
• Network models: i) overview of different strategies (firing vs spiking) to model large-scale neuronal dynamics; ii) Meta-networks; iii) Balanced networks and syn-fire chains; iv) Role of the connectivity in the emerging dynamics; v) overview of the graph theory and metrics for characterizing a network; vi) different kind of connectivity; functional vs structural connectivity; vii) interplay between connectivity and dynamics.
• Computational paradigms: i) Coding and decoding information; ii) Feed-forward and recurrent networks, lateral inhibition.
• Multidimensional data processing and representation: i) The case study of early sensory systems: receptive fields, tuning curves, population activity, read-out mechanisms; ii) Efficient coding and reduction of dimensionality; iii) Optimal decoding methods.
• Computational synthesis of brain information processing: models of “perceptual engines”, potentialities and design examples.

RECOMMENDED READING/BIBLIOGRAPHY

Slides and other distributed material (available through Aulaweb).

Recommended texts:

• Koch and Segev.  Methods in Neuronal Modeling. MIT press, 1999.
• Gerstner and Kistler.  Spiking Neuron Models. Cambridge press, 2002.
• Izhikevich. Dynamical systems in neuroscience. MIT press, 2007.
• Dayan and Abbott. Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems. The MIT Press, 2001.

TEACHERS AND EXAM BOARD

Exam Board

PAOLO MASSOBRIO (President)

SILVIO PAOLO SABATINI (President Substitute)

LESSONS

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

Oral examination and evaluation of the presentation of a scientific paper selected by the student.

ASSESSMENT METHODS

After completing this course, the student will be able to:

• Develop computational models of large-scale neuronal networks.
• Analyze and synthetize neuromorphic processing paradigms at cellular, network, and system level.

Exam schedule