CODE 80586 ACADEMIC YEAR 2021/2022 CREDITS 5 cfu anno 1 BIOENGINEERING 11159 (LM-21) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR CHIM/07 TEACHING LOCATION GENOVA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: CHEMISTRY AND BIOCHEMISTRY TEACHING MATERIALS AULAWEB AIMS AND CONTENT LEARNING OUTCOMES L’insegnamento in questo modulo si propone di fornire allo studente un approfondimento su temi di chimica, chimica di coordinazione e chimica organica con particolare attenzione all’identificazione delle principali classi di composti organici, alla discussione di meccanismi di reazione con aspetti cinetici e termodinamici, e alle relazioni tra struttura e proprietà di macromolecole di sintesi e biomolecole. AIMS AND LEARNING OUTCOMES The course will provide an in-depth knowledge of the structure, reactivity and properties of organic molecules. It is developed through three successive steps: classification and structure of functional groups characterizing the main classes of compounds in organic chemistry and fundamentals on the chemistry of coordination compounds; reactivity and reaction mechanisms for the conversion of different classes of compounds; description of structure, properties and reactivity of polyfunctional macromolecules of biological and biomedical / technological interest. By the end of the course the student should be able to: -describe the main functional groups and classes of compounds in organic chemistry (structure, nomenclature and isomerism), -describe the coordination compounds, -describe, with examples, (bio) macromolecules and polymeric sinthetic and natural structures, -explain the general mechanisms of reactions in organic chemistry, -evaluate, based on its chemical functional groups, the reactivity of an organic compound, -predict the products of specific organic reactions -evaluate the macroscopic properties of simple and complex organic compounds in relation to their structure. TEACHING METHODS Lectures, exercises and discussion of problems on chemical reactions and properties during class hours SYLLABUS/CONTENT Common functional groups in Organic Chemistry, IUPAC nomenclature and classifications of main organic compounds. Single bonds: alkanes, alcohols, ethers, amines. Double bonds: alkenes, carbonyl compounds (aldehydes, ketones, carboxylic acids and functional derivatives of carboxylic acids). Triple bonds: alkynes and nitriles. Aromatic hydrocarbons: benzene and main derivatives. Essentials of nitrogen, sulfur and phosphorus containing organic compounds. Properties. Stereochemistry. Main organic reaction mechanisms: nucleophilic substitution, electrophilic addition, elimination, nucleophilic addition, nucleophilic acyl substitution, chemical reactivity of benzene. Oxidation-reduction reactions. Synthetic polymers: polymerisation reactions and structure-property relationships. Molecules of biological interest: carbohydrates (monosaccharides, disaccharides, polysaccharides), amino acids and proteins, lipids, DNA and RNA. Essentials of coordination compounds. RECOMMENDED READING/BIBLIOGRAPHY Lecture notes, aulaweb, Chemistry reference textbooks: J.McMurry, Fundamentals of Organic Chemistry; W.Brown, T.Poon, Introduction to Organic Chemistry, J.Wiley and Sons; J.G.Smith, Organic Chemistry, McGraw Hill TEACHERS AND EXAM BOARD ELISABETTA FINOCCHIO Ricevimento: By appointment. E-mail: Elisabetta.Finocchio@unige.it, phone: 010.3352919 LESSONS LESSONS START https://corsi.unige.it/11159/p/studenti-orario Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral (partial) exam. The exam related to the first module should be taken before the exam of the second module. The final exam result is the average mark of the two modules marks. ASSESSMENT METHODS After completing this course, the student will be able to manage skills and operating method for the approach of problems related to properties and structure of biomolecules and complexes and their reactivity, focusing on their role in technological and biomedical applications. The oral exam will verify the ability of the student to assign the correct name to simple and complex organic compounds, and to analyze and compare properties and structure of the main classes of compounds in organic chemistry (including polymers, biomacromolecules and complexes). During the exam, the student should also be able to discuss reaction mechanisms and products, describing them in general and critically analyzing specific problems. The correctness and completeness of the answers and also the quality of the exposure, with the use of the appropriate specialized lexicon, will be evaluated. Exam schedule Data appello Orario Luogo Degree type Note 10/01/2022 09:30 GENOVA Orale 08/02/2022 09:30 GENOVA Orale 07/06/2022 09:30 GENOVA Orale 30/06/2022 09:30 GENOVA Orale 19/07/2022 09:30 GENOVA Orale 09/09/2022 09:30 GENOVA Orale