| CODE | 67362 |
|---|---|
| ACADEMIC YEAR | 2022/2023 |
| CREDITS |
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| SCIENTIFIC DISCIPLINARY SECTOR | MED/04 |
| LANGUAGE | Italian |
| TEACHING LOCATION |
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| SEMESTER | 1° Semester |
| PREREQUISITES |
Prerequisites
You can take the exam for this unit if you passed the following exam(s):
Prerequisites (for future units)
This unit is a prerequisite for:
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| TEACHING MATERIALS | AULAWEB |
The course gives students the fundamental elements of pathophysiology, which are essential for the successive comprehension of clinical medical sciences.
Physiopathology is a branch of medicine that combines physiology and pathology especially in the study of altered bodily function in disease. The learning outcome is the knowledge of the main physiopathological mechanisms of organs and systems, in order to recognize the mechanisms and causes of their malfunction, and to be able to interpret the symptoms, which will be exposed to the students in the successive clinical courses
Knowledge of the main physiopathological mechanisms of organs and systems, with particular regard to blood, liver, kidney, respiratory and digestive systems, some aspects of endocrinology and metabolism, and the physiopathology of neoplasms.
basic knowledge in anatomy, histology, biochemistry, immunology and physiology
Lectures, with any possible dialectic interaction with students
In case of sanitary emergency, lessons will switch to remote learning
Hematopoiesis
The hematopoietic and mesenchymal stem cells
Bone marrow transplant / HSC
Erythropoiesis
Anemias. Classification and general considerations
Bone marrow aplasia
B12 and folate deficiency anemia
Thalassemia, Iron deficiency anemia
Auto and alloimmune hemolytic anemias
Paroxysmal nocturnal hemoglobinuria
Hemostasis and bleeding diathesis
Abnormalities of the vascular wall, thrombocytopenia
Alterations of clotting factors
The neoplastic transformation; benign and malignant tumors; metastasis
Local and systemic effects, paraneoplastic syndromes
Molecular basis of cancer
Oncogenes and related neoplastic diseases
Oncosuppressors and related neoplastic diseases
Epidemiology
Risk and prognostic factors, stage, grade
Cancer stem cells (CSCs)
Hematological neoplasms: classification and general considerations
Myeloid neoplasms
Lymphoid neoplasms
Angiogenesis and tumor microenvironment
Anti-tumor immune response
Neoplasm and inflammation
Atherosclerosis
Ischemic heart disease
Rheumatic fever
Hypertension
Heart failure
Examples of pathologies of the grastrointestinal and respiratory systems
Diabetes
Pathogenesis of diabetes complications
acute complications
chronic complications
Renal pathophysiology
Kidney failure
Evaluation of renal failure
Hydro saline balance (water)
Salt and water balance (sodium)
The water and salt balance (potassium)
The salt and water balance (calcium)
The hydro saline balance (phosphorus)
The acid-base balance: general information
Metabolic disturbances of the acid-base equilibrium
Dyslipidemias
Alterations of carbohydrate metabolism (lactose intolerance, galactosemia)
Changes in nitrogen metabolism (gout)
Alterations in nitrogen metabolism (porphyrias)
Alterations in nitrogen metabolism (phenylketonuria)
Alterations in nitrogen metabolism (hyperhomocysteinemia)
Methemoglobinemias
Etiopathogenesis of liver damage
Acute and chronic hepatitis
Cirrhosis of the liver
Hepatic insufficiency
Jaundice
Metabolic liver disease
Non-alcoholic steatohepatitis
Metal storage liver disease
Robbins & Cotran Pathologic Basis of Disease, Elsevier
The didactic material is available in pdf format for download (https://www.aulaweb.unige.it).
The aim of the course is also to familiarize students with online biomedical scientific literature (https://www.ncbi.nlm.nih.gov/pubmed)
Students with SLD, disability or other special educational needs certification are strongly encouraged to contact the teachers at the beginning of the course to agree on teaching methods which, respecting the teaching objectives, take into account individual learning methods and provide suitable compensatory instruments.
Office hours: By appointment Cristina.Bottino@unige.it
Office hours: For appointments, contact the Professor via email at: Nicola.Traverso@unige.it. The teacher's office is located in the General Pathology Section of DIMES, Via Leon Battista Alberti 2, 1st floor, 16132 Genoa Nicola Traverso is the Coordinator of the Integrated Course of Clinical Pathology and Immunohematology
Office hours: The reception of the students is agreed from time to time, according to the needs and deadlines, by e-mail to the following address: Cinzia.Domenicotti@unige.it The office is located at General Pathology Section - DIMES via LB Alberti 2- Genoa tel +39 010 3538830
CRISTINA BOTTINO (President)
NICOLA TRAVERSO (President)
ANNA MARIA BASSI
CINZIA MARIA DOMENICOTTI
1st semester, 3rd year
All class schedules are posted on the EasyAcademy portal.
The end-of-course exam aims to evaluate the achievement of the educational objectives of the course. The exams take place on the dates indicated in the calendar. Verification is oral, conducted by two teachers for each student. The grade is assigned as a weighted average. The teachers verify the achievement of the educational objectives by asking diversified questions relating to the programs actually carried out during the lesson hours. When the educational objectives have not been achieved, the student is invited to better verify his knowledge and to take the exam again in its entirety. There are no student reception hours, but students can contact the teachers by email in order to make an appointment for further explanations.
Exam Commission: Proff. Cristina Bottino, Nicola traverso, Cinzia Domenicotti
In case of changes in the sanitary and epidemiological situation, the exams will be carried out remotely (TEAMS).
Verification of learning takes place only through the final exam which aims to verify the actual acquisition, by the student, of the expected learning outcomes. In order to pass the exam, with a score of not less than 18/30, the student must demonstrate that they know and connect the topics covered during the course
The following contribute to the final mark expressed out of thirty:
- Ability to deal with the requested topics in a transversal and critical manner;
- Correctness, clarity, synthesis and fluidity of presentation;
- Mastery of the subject;
- Adoption of appropriate terminology
The mark of 30/30 with possible honors will be awarded when the knowledge / skills of the subject are excellent.
Students with SLD or other regularly certified special educational needs will be able to agree on written or oral modalities with the teacher, by contacting the teachers at least 10 days before the exam. They can also take advantage of 30% additional time.
| Date | Time | Location | Type | Notes |
|---|---|---|---|---|
| 21/12/2022 | 14:00 | GENOVA | Orale | Preappello riservato SOLO ed ESCLUSIVAMENTE agli studenti iscritti al 3 e 4 anno. Devono essere rispettate le propedeuticità dell'anno di iscrizione a medicina Gli studenti che non soddisfano i criteri di cui sopra non potranno sostenere l'esame SEDE ESAME: Aula 3 - Edificio 6 - Polo didattico Alberti L'elenco degli studenti con data e ora dell'esame sarà pubblicato sul team delle lezioni |
| 09/01/2023 | 09:00 | GENOVA | Orale | SEDE ESAME: Auletta patologia generale |
| 30/01/2023 | 09:00 | GENOVA | Orale | SEDE ESAME: Aula grande di patologia Generale |
| 20/02/2023 | 14:00 | GENOVA | Orale | Gli studenti di odontoiatria sosterranno l'esame lunedì, ore 14.30, biblioteca di patologia Per gli studenti di medicina gli esami inizieranno mercoledì 22 febbraio (lettera estratta F). L'elenco degli studenti con data, ora e sede dell'esame è disponibile sul canale teams bw6jvck. Eventuali scambi 1:1 tra gli studenti devono essere comunicati in sede d'esame Nel caso del superamento di prove propedeutiche a fisiopatologia e non ancora registrate in carriera, gli studenti devono presentare una dichiarazione firmata dal docente |
| 06/04/2023 | 09:00 | GENOVA | Orale | Appello straordinario riservato a studenti IN CORSO CON OBBLIGO DI FREQUENZA iscritti al 3 o 4 anno di medicina SEDE: Aula 5 - Edificio 6 - Polo didattico Alberti ore 9.30 ANTONINI ALESSIO 4683504 API ANNA 4821940 BARBAGELATA BEATRICE 5000733 BONVICINO VALENTINA 5103177 BRAMBILLA FEDERICO 4932480 CARONI JUAN DAVIDE 4825108 COSTA ALESSANDRA 4834799 DE MORO FRANCESCA 4805704 DEL GAUDIO DENISE 5102220 FADDA FEDERICA 5005464 FOTSO KENGNE WILFRIED BORIS 4799742 GHISILIERI JORGE MANUEL 4820169 GRANDIS ALBERTO 4327798 ore 14.30 KHALIFA NORHAN 4371368 MARSANO NICOLÒ 5107137 ORSOLINO VIOLA 5017234 PANINA CHIARA 4815231 PASQUALI SUSANNA 5102451 PIASTRI FRANCESCA 5000744 PIETRAFRACCIA CHIARA EMMA 4822336 PROSERPIO CHIARA 5103111 RISSO VIRGINIA 4943819 RIVA ANNALISA 5109315 SQUERI CAROLA 4624929 TARÌ ALICE 5115277 VEGLIO VALENTINA 5017971 VINCI GIADA 5102439 |
| 16/05/2023 | 09:00 | GENOVA | Orale | Appello riservato a studenti fuoricorso o ripetenti senza obbligo di frequenza SEDE: Auletta Patologia generale |
| 05/06/2023 | 14:30 | GENOVA | Orale | SEDE auletta chirurgica ORARIO h 14.30 |
| 26/06/2023 | 09:00 | GENOVA | Orale | |
| 17/07/2023 | 09:00 | GENOVA | Orale | |
| 04/09/2023 | 09:00 | GENOVA | Orale | |
| 18/09/2023 | 09:00 | GENOVA | Orale |
Attendance allows the student to better learn the contents of the course because the teacher provides detailed explanations during the lessons and frames the topics with continuous references to the most current discoveries in the field of the subject. The teaching material is available online (Teams or Aulaweb)