|SCIENTIFIC DISCIPLINARY SECTOR||BIO/14|
Neuropharmacology is the part of neuroscience which is devoted to the study of the drugs able to modulate the functioning of the central nervous system, and in particular within the brain. Neuropharmacology goal is the understanding of how impulses and signals within the brain are altered in pathological conditions and can be restored after drug treatment
The aim of the course is to provide the students with knowledge about the main classes of drugs active on the central nervous system. The course will be focused to study the main pharmacological strategies used to modulate the neurochemical and behavioral responses to affect the pathogenetic mechanisms of the main CNS diseases.
The course will be focused to study the main pharmacological strategies used to modulate the neurochemical and behavioral responses to affect the pathogenetic mechanisms of the main CNS diseases. The most used experimental models for the study of drugs in neurological diseases will also be addressed
The student will know the symptoms related to the main neurotransmitter alterations and the therapeutic possibilities of the pharmacological modulation of their activity, with particulkar attention to:
serotoninergic neurotransmission in depression and pharmacological modulation
GABaergic neurotransmission in anxiety syndromes and pharmacological modulation
oppioidergic neurotransmission in pain control and pharmacological modulation
dopaminergic neurotransmission in psychosee and M. of Parkinson and pharmacological modulation
cholinergic neurotramsmission in dementia and pharmacological modulation
neurotransmitter nechanisms in reward and drug dependnece and pharmacological modulation
Neuropharmacology course will comprise 2,5 CFU (24) hours of frontal teaching.
According to the didactic rules of the Medical-pharmaceutical Biotechnology Master course, the frequency is mandatory.
1) Pharmacology of nociceptive system
2) Pharmacology of the cannabinoid system
3) Pharmacology of the depression
4) Pharmacology of the anxiety (anxiolytics, sedative hypnotic drugs)
5) Pharmacology of the psychosis (typical and atypical drugs)
6) Pharmacology of the epilepsies
7) Pharmacology of the Parkinson disease
8) Pharmacology of the dementias
9) Pharmacology of the drug abuse and dependence
All the slides used during the frontal lessons will be made available via Aulaweb site, before the respective lesson.
Moreover, the following texts are recommnended to in depth address the course topics:
S. Govoni, L. Frattola, G. Racagni, E. Smeraldi. Neuropsicofarmacologia. UTET
F. Clementi, G. Fumagalli. Farmacologia generale e molecolare. UTET.
Office hours: Unit of Pharmacology ( with focuses on psychoactive drugs) Meetings will students will be held at ex inst. of Pharmacology Viale Benedetto XV, 2. Genova, ground floor Phone +39 0103538884. cell 3291484399. email: email@example.com Students may also want to use the platform Microsoft teams ( code 3f12f6).
The exam will be held as oral interogation about the topics discussed during the course.
Students can choose among 3 sessions during the winter semester (in January and february) and 4 sessions in the summer one (June, July and September)
The exam will be performed by the presentation by the students of topics reported in the syllabus and discussed during the frontal lessons. In depth analyses and relationship with other topics can be requested. The discussion will have the goal to assess the not only the level of knowledge gained by the student but also its ability to critically analyze the main neuropharmacology-related issues.