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NEUROPHARMACOLOGY

CODE 98818
ACADEMIC YEAR 2022/2023
CREDITS
  • 2.5 cfu during the 2nd year of 10598 MEDICAL-PHARMACEUTICAL BIOTECHNOLOGY(LM-9) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR BIO/14
    LANGUAGE English
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 2° Semester
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    Neuropharmacology is the part of neuroscience which is devoted to the study of the drugs able to modulate the functioning of the central nervous system, and in particular within the brain. Neuropharmacology goal is the understanding of how impulses and signals within the brain are altered in pathological conditions and can be restored after drug treatment

    AIMS AND CONTENT

    LEARNING OUTCOMES

    The aim of the course is to provide the students with knowledge about the main classes of drugs active on the central nervous system. The course will be focused to study the main pharmacological strategies used to modulate the neurochemical and behavioral responses to affect the pathogenetic mechanisms of the main CNS diseases.

    AIMS AND LEARNING OUTCOMES

    The course will be focused to study the main pharmacological strategies used to modulate the neurochemical and behavioral responses to affect the pathogenetic mechanisms of the main CNS diseases. The most used experimental models for the study of drugs in neurological diseases will also be addressed

    The student will know the symptoms related to the main neurotransmitter alterations and the therapeutic possibilities of the pharmacological modulation of their activity, with particulkar attention to:

    serotoninergic neurotransmission in depression and pharmacological modulation

    GABaergic neurotransmission in anxiety syndromes  and pharmacological modulation

    oppioidergic neurotransmission in pain control and pharmacological modulation

    dopaminergic neurotransmission in psychosee and  M. of Parkinson and pharmacological modulation

    cholinergic neurotramsmission in dementia and pharmacological modulation

    neurotransmitter nechanisms in reward and drug dependnece  and pharmacological modulation

    TEACHING METHODS

    Neuropharmacology course will comprise 2,5 CFU (24) hours of frontal teaching.

    According to the didactic rules of the Medical-pharmaceutical Biotechnology Master course, the frequency is mandatory.

    SYLLABUS/CONTENT

    1) Pharmacology of nociceptive system

    2) Pharmacology of the cannabinoid system

    3) Pharmacology of the depression

    4) Pharmacology of the anxiety (anxiolytics, sedative hypnotic drugs)

    5) Pharmacology of the psychosis (typical and atypical drugs)

    6) Pharmacology of the epilepsies

    7) Pharmacology of the Parkinson disease

    8) Pharmacology of the dementias

    9) Pharmacology of the drug abuse and dependence

    RECOMMENDED READING/BIBLIOGRAPHY

    All the slides used during the frontal lessons will be made available via Aulaweb site, before the respective lesson.

    Moreover, the following texts are recommnended to in depth address the course topics:

    S. Govoni, L. Frattola, G. Racagni, E. Smeraldi. Neuropsicofarmacologia. UTET 

    F. Clementi, G. Fumagalli. Farmacologia generale e molecolare. UTET.

    TEACHERS AND EXAM BOARD

    LESSONS

    LESSONS START

    Second semester

    Class schedule

    NEUROPHARMACOLOGY

    EXAMS

    EXAM DESCRIPTION

    The exam will be held as oral interogation about the topics discussed during the course.

    Students can choose among 3 sessions during the winter semester (in January and february) and 4 sessions in the summer one (June, July and September)

    ASSESSMENT METHODS

    The exam will be performed by the presentation by the students of topics reported in the syllabus and discussed during the frontal lessons. In depth analyses and relationship with other topics can be requested. The discussion will have the goal to assess the not only the level of knowledge gained by the student but also its ability to critically analyze the main neuropharmacology-related issues.