CODE | 58087 |
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ACADEMIC YEAR | 2022/2023 |
CREDITS |
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SCIENTIFIC DISCIPLINARY SECTOR | BIO/13 |
LANGUAGE | Italian |
TEACHING LOCATION |
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SEMESTER | 1° Semester |
MODULES | This unit is a module of: |
TEACHING MATERIALS | AULAWEB |
The course consists of frontal lectures of cell biology and general genetics. At the end of the course students will be accompanied in the laboratory where the teacher works to see how a research laboratory is organized. In addition, students will be able to attend on-going experiments related to the exam program.
The course promotes the knowledge of the organization and functioning of eukaryotic cells and the understanding of inheritance transmission mechanisms.
At the end of the course the student knows:
- living matter composition and organization in its biological elementary units and basic cellular processes of living organisms.
- organization of genetic information, its transmission and expression in eukariotic cells and interaction between ambient and genome.
- cellular proliferation and organism reproduction and principal mechanisms that underly to the continuity and variance of organisms.
frontal lectures and visit to a research laboratory
Cell Biology
living cell composition
Metabolic energy
ATP production from organic molecules
Cellular components biosynthesis
The cell:
Asexual and sexual reproduction
Cell cycle and mitosis
Signal transmission:
Oncogenes, tumor suppressor genes, oncogenic viruses
Cell death and cell renewal:
The extracellular matrix:
Cellular interactions:
General Genetics
The gene theory and Mendelism
Mendel's laws:
Non-Mendelian inheritance and variations in Mendelian ratio:
The chromosomal theory of inheritance:
The chromosome nondisjunction
Chromosomal translocations
Human chromosomal syndromes
Concatenation and gene mapping:
The anatomy of the human genome
Character Transmission
Dominance and recessive
Autosomic characters
Characters related to sex
The genealogical trees
Penetration and Expressivity
The biochemical nature of the gene:
DNA duplication
Genetic mutations
The transcription of RNA
Protein biosynthesis
L'essenziale di Biologia Molecolare della Cellula, Alberts et al., Zanichelli
Biologia Molecolare della cellula. Harvey Lodish et al., Zanichelli
Genetica, un approcciomolecolare. Peter J. Russel, Pearson
Genetica - principi di analisiformale. Anthony J. F. Griffiths et al.
Office hours: by appointment
PAOLO MALATESTA
SARA TAVELLA (President and Coordinator of Integrated Course)
All class schedules are posted on the EasyAcademy portal.
Date | Time | Location | Type | Notes |
---|---|---|---|---|
31/01/2023 | 09:00 | GENOVA | Scritto | |
14/02/2023 | 09:00 | GENOVA | Scritto | |
13/06/2023 | 09:00 | GENOVA | Scritto | |
04/07/2023 | 09:00 | GENOVA | Scritto | |
19/09/2023 | 09:00 | GENOVA | Scritto |