CODE | 98799 |
---|---|
ACADEMIC YEAR | 2022/2023 |
CREDITS |
|
SCIENTIFIC DISCIPLINARY SECTOR | BIO/10 |
LANGUAGE | English |
TEACHING LOCATION |
|
SEMESTER | 1° Semester |
TEACHING MATERIALS | AULAWEB |
The course is structured in two modules: Organ Biochemistry and Diagnostic Biotechnology. The Biochemistry module aims to analyze in details some aspects of protein biochemistry and tissue/ specialized organ biochemistry. During the laboratory, selected innovative biochemical methods and technologies will be discussed, using examples from the literature. The module of Diagnostic Biotechnology, aims to introduce students to the methods derived from basic biotechnologies that were transferred to medical diagnostics; know the main analyses of clinical biochemistry and their interpretation to verify metabolism and function of different organs.
The course aims to provide a deeper knowledge about protein functions, with a particular focus about the role of post-translational modifications (PTM), protein sorting and proteostasis in physiological and pathological conditions. Moreover, it will analyze at the biochemical and molecular level the specialized functions of organs and tissues and their complex relationships and the control systems in physiological conditions. The course will also focus on the understanding on some of the basic mechanisms responsible for alterations of homeostasis and the onset of diseases.
At the end of the course the student will be able to:
A good knowledge of the macromolecule structures, of the metabolic pathways and of signal transduction mechanisms is required.
The Human biochemistry module consists in lectures on the indicated topics. The Laboratory will be practical and it will be held in Polo biotech; students will be required to develop a protocol aimed to study PTM or effects of alterations in PQC.
1 .Protein biochemistry
2. Organ biochemistry
3. Biochemistry of cancer cells
4. Biochemistry of the sensory systems (vision, olfaction, hearing, touch, taste)
Slides and additional material for the study will be provided usig aualweb
Office hours: The teacher receives by appointment at Biochemistry - DIMES, Viale Benedetto XV No. 1, first floor, Genoa. The talks may take place, by appointment, also via Skype For appointments please send an email to: tonetti@unige.it.
Office hours: By appointment by email: santina.bruzzone@unige.it Office: DIMES, Section of Biochemistry, Viale Benedetto XV, 1 (Genova) Phone: 0103538161
SANTINA BRUZZONE (President)
MICHELA TONETTI (President)
MIRKO MAGNONE
LAURA STURLA
VALERIA VISCONTI
All class schedules are posted on the EasyAcademy portal.
The Human biochemistry exam will be written test with 32 multiple choice questions (0.5 marks each). The exam is positively evaluate with a score of 18/30 or higher. The score will be used to calculate the final mark, using the mean with the one obtained in the Clinical Biotechnology exam.
The questions proposed in the written exam will be constructed in such a way evaluate student knowlledge, but also to investigate the student biochemical reasoning and to evaluate the skills and competences acquired according to the objectives of the course.