CODE 58032 ACADEMIC YEAR 2022/2023 CREDITS 1 cfu anno 1 MEDICINA E CHIRURGIA 8745 (LM-41) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/12 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester MODULES Questo insegnamento è un modulo di: BIOCHEMISTRY TEACHING MATERIALS AULAWEB AIMS AND CONTENT AIMS AND LEARNING OUTCOMES Provide the basic knowledge to understand the meaning of the main laboratory parameters that constitute the "chemical-clinical profile", a kind of "physical examination" by means of laboratory tests. Acquire basic knowledge about the units of measurement of these parameters and their dynamic range in pathological conditions. Identify deviations from the norm indicative of pathology. TEACHING METHODS Face-to-face or video-recorded lessons (in presence), available on aulaweb, depending on anti-covid guidelines by the University of Genova. During the lectures, the main laboratory tests related to the program topics, the unit of measurement and normal values, and the extent of deviation from normality in some examples of diseases will be presented. SYLLABUS/CONTENT The topics covered in the clinical biochemistry part of the biochemistry 2 course concern clinical aspects of glucose, lipid and nitrogen metabolisms covered in the course; in particular, the following topics will be explored: the chemistry-clinical profile (complete blood count, serum protein electrophoresis, non-protein nitrogen, serum enzymes), liver function and necrosis tests, general markers of inflammation, laboratory tests in dyslipidemia and diabetes mellitus, muscle biochemistry, indicators of nutritional status. RECOMMENDED READING/BIBLIOGRAPHY on-line available slides and Biochemistry with clinical aspects, Devlin, Edises Elementi di biochimica clinica, M. Ciaccio, Edises TEACHERS AND EXAM BOARD ELENA ZOCCHI Ricevimento: On-demand tutorials and questions, either in presence (at DIMES, Sez. Biochimica, Viale Benedetto XV 1, 1st floor) or via the Teams platform, by appointment (ezocchi@unige.it and bagnasco@unige.it). Exam Board SANTINA BRUZZONE (President) GIANLUCA DAMONTE (President) MICHELA TONETTI (President) MIRKO BENVENUTI ELENA ZOCCHI (President and Coordinator of Integrated Course) LESSONS LESSONS START For lessons start and timetable go to the link: https://easyacademy.unige.it/portalestudenti/ Please check the module Aulaweb page for timetable updates dependent on the sanitary and epidemic situation Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The exam will verify the attainment of the teaching objectives, by means of a written, multiple choice test (31 questions), performed live in the classroom or on a digital platform, depending on the prescriptions imposed by the SARS-CoV2 emergency. The final grade is expressed in degrees (up to 30, with the possibility of the "cum laude"), and the exam will be passed with at least 18/30 points. Both parts of the Biochemistry 2 exam (metabolic biochemistry + clinical biochemistry) must be passed in the same exam session. ASSESSMENT METHODS The exam will verify the achievement of the formative objectives; in particular, it will ascertain the student's knowledge of the clinical meaning of the biochemical-clinical parameters presented during the lessons, of the unit of measure in which they are expressed and of their dynamic range in the main pathologies for which they represent a diagnostic-prognostic tool. The ability to choose, among some proposed tests, those suitable to solve a specific diagnostic question, and the ability to identify deviations from the norm indicative of pathology, will be evaluated. Please refer to the AulaWeb instance specific to the teaching for possible updates due to changes in the health and epidemiological situation. Exam schedule Data appello Orario Luogo Degree type Note 09/01/2023 10:00 GENOVA Orale 09/01/2023 10:00 GENOVA Orale 13/01/2023 14:00 GENOVA Scritto 26/01/2023 09:30 GENOVA Orale 03/02/2023 14:00 GENOVA Scritto 09/02/2023 09:30 GENOVA Orale 23/02/2023 09:30 GENOVA Orale 23/02/2023 10:00 GENOVA Orale 24/02/2023 14:00 GENOVA Scritto 17/04/2023 12:30 GENOVA Orale 17/04/2023 12:30 GENOVA Orale 01/06/2023 14:00 GENOVA Scritto 05/06/2023 09:30 GENOVA Orale 05/06/2023 10:00 GENOVA Orale 23/06/2023 14:00 GENOVA Scritto 26/06/2023 09:30 GENOVA Orale 26/06/2023 10:00 GENOVA Orale 07/07/2023 14:00 GENOVA Scritto 10/07/2023 09:30 GENOVA Orale 10/07/2023 10:00 GENOVA Orale 25/07/2023 09:30 GENOVA Orale 25/07/2023 10:00 GENOVA Orale 15/09/2023 14:00 GENOVA Scritto 18/09/2023 09:30 GENOVA Orale 18/09/2023 10:00 GENOVA Orale FURTHER INFORMATION On-demand tutorials and questions, either in presence (at DIMES, Sez. Biochimica, Viale Benedetto XV 1, 1st floor) or via the Teams platform, by appointment (ezocchi@unige.it).