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GENERAL AND INORGANIC CHEMISTRY (PCT)(MD)

CODE 55401
ACADEMIC YEAR 2022/2023
CREDITS
  • 10 cfu during the 1st year of 8451 CHIMICA E TECNOLOGIA FARMACEUTICHE (LM-13) - GENOVA
  • SCIENTIFIC DISCIPLINARY SECTOR CHIM/03
    TEACHING LOCATION
  • GENOVA
  • SEMESTER 1° Semester
    PREREQUISITES
    Prerequisites (for future units)
    This unit is a prerequisite for:
    • Pharmaceutical chemistry and technology 8451 (coorte 2022/2023)
    • DRUGS ANALYSIS I 80443
    • SINTESI DEI FARMACI (CON ESERC.) 80453
    • MEDICINAL AND TOXICOLOGICAL CHEMISTRY I 80446
    • PHARMACEUTICAL AND TOXICOLOGICAL CHEMISTRY II (PCT) 67558
    • INSTRUMENTAL ANALYSIS OF DRUGS (WITH PRACTICE) 80452
    • PLANT BIOLOGY AND BIOACTIVE COMPOUNDS (I.C.)(PCT MD) 80447
    • BIOCHEMISTRY AND APPLIED BIOCHEMISTRY (I.C.)(PCT MD) 80520
    • ANALYTICAL CHEMISTRY (PCT)(MD) 55403
    • ORGANIC CHEMISTRY II (PCT)(MD) 60828
    • PHYSICAL CHEMISTRY (MD) 60821
    • DRUGS ANALYSIS II 80445
    • PHARMACEUTICAL TECHNOLOGY AND LAW I (PCT) 67569
    • PHYSICS METHODS IN ORGANIC CHEMISTRY (MD) 64193
    • PHARMACOLOGY AND PHARMACOTHERAPY (PCT) 67563
    • GENERAL PHARMACOLOGY AND TOXICOLOGY (PCT MD) 64200
    • ORGANIC CHEMISTRY I (PCT)(MD) 60822
    • TECNOLOGIA E LEGISLAZIONE FARMAC. II (CON ESERC.)(LM CTF) 67615
    • CHIMICA FARMACEUTICA APPLICATA (LM) 67617
    • COSMETIC PRODUCTS 67501
    • CHIMICA DEGLI ALIMENTI (CTF)(LM) 64194
    TEACHING MATERIALS AULAWEB

    OVERVIEW

    The General and Inorganic Chemistry course plays an important role in the education and training of CTFs (Pharmaceutical Chemists and Technologists) and Pharmacists since it provides the basic chemical knowledge, required for the understanding of the chemical disciplines over the following years; moreover, it allows to acquire the scientific language and the calculation skills required in the professional practice.

    AIMS AND CONTENT

    LEARNING OUTCOMES

    This course aims to provide the basic knowledge of chemistry, necessary for the further studies. The fundamentals for the correct comprehension of matter and its transformations are the subject of this course.

    The learning outcomes are, in addition to the acquisition of the basic knowledge, the ability of using scientific language and of solving numerical problems, by applying the acquired notions to real cases.

     

    AIMS AND LEARNING OUTCOMES

    This course aims to provide the basic knowledge of chemistry, necessary for the further studies. The fundamentals for the correct comprehension of matter and its transformations are the subject of this course. In particular:

    - matter and its structure (atomic structure, chemical bonds, inorganic compounds, nomenclature, states of matter);

    - principles of chemical thermodynamics;

    -  solutions;

    - chemical reactions;

    - chemical equilibrium;

    - electrochemistry;

    - periodic table and main chemical properties of the most important elements and inorganic compounds.

    The learning outcomes are, in addition to the acquisition of the basic knowledge, the ability of using scientific language and of solving numerical problems, by applying the acquired notions to real cases.

    TEACHING METHODS

    The teaching is based on class lessons (80 hours). The lessons deal the whole programme; the teacher presents and solves problems.

    In particular cases, such as pandemic situations, the lessons might be held by remote (only remote learning or blended mode), following the University guidelines.

    Didactic materials are provided in Aulaweb, in order to facilitate the study; exercises for checking the knowledge level are proposed. Students may upload their exercises and receive feedback by the teacher.

    SYLLABUS/CONTENT

    • Introduction to Chemistry. Elements, compounds and mixtures. Solutions and concentration. Rules of chemical nomenclature. Chemical reactions. Stoichiometry.
    • Gas state. The equation of state of ideal gas. Mixtures of gases and Dalton’s law of partial pressure. The real gases and Van der Waals equation.
    • Thermodynamics. Heat of reaction and enthalpy. Enthropy. Gibbs free energy and spontaneous reactions.
    • Atom. Atomic structure. Atomic orbitals. Electrons and orbitals. Periodic table.
    • Chemical bond. Ionic bond. Covalent bound. Electronegativity. Lewis structures. The VSEPR theory. Hybrid orbitals. Intermolecular forces.
    • Liquid state and solid state. Liquids. Solids. Metallic bond. Phase transitions and phase diagrams for single-component systems.
    • Solutions. Solubility. Ideal solution and Raoult’s law. Colligative properties. Electrolytes. Degree of dissociation. Conductivity of electrolyte solutions.
    • Chemical kynetics. Reaction rate. Collision theory. Factors affecting the rate of reactions. Kinetic equation. Catalysis.
    • Chemical equilibrium. Law of mass action. Equilibrium constant. Le Chatelier’s principle. Homogeneous and heterogeneous equilibrium.
    • Acids and bases. Theories of: Arrhenius, Brønsted-Lowry and Lewis. Strength of acids and bases. Acidity of aqueous solutions: pH. pH indicators. Hydrolysis. Buffer solutions. Solubility equilibrium. Complexes.
    • Electrochemistry. Electrodes and galvanic cells. Reduction potentials and Nernst equation. Electrolysis. Faraday’s laws. Accumulators.
    • Inorganic chemistry. Hydrogen. Main characteristics of the elements of 1, 2, 13, 14, 15, 16, 17, 18 Groups and their most representative compounds. Characteristics of the elements of d-block and representative compounds.

    RECOMMENDED READING/BIBLIOGRAPHY

    The recommended book is:

    - Peter Atkins, Loretta Jones, “CHIMICA GENERALE”, Ed. Zanichelli.

    Other books of General and Inorganic Chemistry at university level can be used, e.g.:

    - Kotz, Treichel, Townsend, Treichel “CHIMICA”, VII ed., Ed. Edises

    - Brown, Lemay, Bursten, Murphy, Woodward, “FONDAMENTI DI CHIMICA”, Ed. Edises

    - Casarin, Casella, D'Agostino, Filippi, Grandinetti, Purrello, Re, Speranza, "CHIMICA GENERALE E INORGANICA" a cura di M. Speranza, Ed. Edi-ermes

    - Petrucci, Herring, Madura, Bissonnette, “CHIMICA GENERALE. Principi ed applicazioni moderne" (+ complete solutions manual), Ed. Piccin 

    TEACHERS AND EXAM BOARD

    Exam Board

    GIULIANA DRAVA (President)

    VALERIO VOLIANI

    MONICA CASALE (Substitute)

    RICCARDO LEARDI (Substitute)

    VINCENZO MINGANTI (Substitute)

    PAOLO OLIVERI (Substitute)

    PAOLA RIANI (Substitute)

    LESSONS

    Class schedule

    All class schedules are posted on the EasyAcademy portal.

    EXAMS

    EXAM DESCRIPTION

    The exam consists of two compulsory parts: a written test followed by an oral test.

    The written test consists in numerical problems and chemical reactions.

    After the correction, the participants can view their test and comment it with the professor.

    The minimum score to be admitted to the oral exam is 18/30.

    If the score is LESS THAN 12, students are not permitted to repeat the failed test in the next date, if this falls within 20 days.

    The oral exam is conducted by two professors of the academic staff; it covers the whole course content and it takes 30 minutes approximately, for an average student.

    In particular sitiations such as health emergency, according to the University guidelines, the exams can be held remotely via Teams. In this case, precise indications will be communicated to students via AulaWeb platform.

    ASSESSMENT METHODS

    The exam aims to assess:

     - the knowledge and comprehension of the discipline (test)

    - the acquisition of a correct scientific language (oral exam);

    - general and specific problem-solving skills in chemistry (test and oral exam).

    Exam schedule

    Date Time Location Type Notes