OVERVIEW

The integrated course of Etiology and Pathogenesis of Diseases is divided in five modules, extending over the two semesters: Applied Biology (General Genetics), Molecular Biology, Medical Genetics (Human Genetics), General Pathology, and Microbiology. 
This course aims to introduce the student to the knowledge about the etiology and the pathogenesis of the diseases in humans both at the cellular and at the molecular levels.

AIMS AND CONTENT

LEARNING OUTCOMES

The Integrated course aims to: deepen the basic knowledge of molecular biology; understand the principles of molecular diagnostics for Mendelian traits and diseases as well as the underlying mechanisms and consequences of gene mutations; deepen the general basis of inheritance; know the fundamental study methods of complex hereditary diseases; introduce the student to the knowledge of the etiology and pathogenetic mechanisms of diseases in humans and to analyze their main cellular and molecular aspects; deepen the pathogenic effects of metabolic alterations, toxic substances and ionizing radiations; study the biology of pathogenic microorganisms and their possible effects on host cells and tissues; analyze the various immunological mechanisms involved in the immune responses and the pathologies associated to an altered function of the immune system.

PREREQUISITES

In order to deal with the contents of the course, students should have a good knowledge in the fields of biochemistry, cellular biology, human anatomy, and histology. 

TEACHERS AND EXAM BOARD

Exam Board

WILLIAM BRUNO (President)

VINCENZO DI PILATO (President)

GUIDO FERLAZZO (President)

PAOLA GHIORZO (President)

GABRIELLA PIETRA (President)

ALDAMARIA PULITI (President)

SONIA SCARFI' (President)

CINZIA MARIA DOMENICOTTI

ANNA MARCHESE

LORENZA PASTORINO

GABRIELLA PIATTI

CLAUDIA CANTONI (President and Coordinator of Integrated Course)

EXAMS

EXAM DESCRIPTION

For the modules carried on in the first semester (Applied Biology, Molecular Biology, Medical Genetics), the exam is an oral one. The oral examination consists of a 20-30 minutes interview in the presence of the course teachers. The student, in the presence of the committee, should demonstrate the ability to critically discuss all the subjects covered in the questions. Through the discussion of different topics, including basic genetic exercises and pedigrees interpretation, the committee verifies the fulfillment of the expected learning outcomes.  The mark 30/30 with honors will be assigned when the knowledge of the subject is excellent.

For the modules carried on in the second semester (Pathology and Microbiology), the exam is an oral one. Students are allowed to undergo the oral examination only if they have passed the test concerning the modules of the first semester with at least 18/30 (this mark is valid for 18 months).

The oral examination consists of a 30 minutes interview in the presence of the course teachers. The student, in the presence of the committee, should demonstrate the ability to critically discuss all the subjects covered in the questions. Through the discussion of different topics, the committee verifies the fulfillment of the expected earning outcomes.

At the end of the oral examination, teachers elaborate a mark deriving from the weighted mean of the partial/preliminary marks and from an overall judgment/evaluation of the student.

The mark 30/30 with honors will be assigned when the knowledge of the subject is excellent.

If necessary, the exams could be carried out remotely in online mode using the Teams platform.

ASSESSMENT METHODS

Verification of learning is carried out through the oral exam, aimed at verifying the real acquisition by the student of the expected learning outcomes.
In order to pass the exam the student will have to demonstrate a good knowledge of the etiological basis and the pathogenic mechanisms of diseases I humans and the ability to analyze their main cellular and molecular aspects;
The following items will contribute to the final mark:
- ability to critically discuss the requested topics;
- accuracy, clarity, synthesis and fluency;
- competence in the subject;
- speaking ability and correct use of terminology.

Exam schedule