CODE 60821 ACADEMIC YEAR 2023/2024 CREDITS 8 cfu anno 2 CHIMICA E TECNOLOGIA FARMACEUTICHE 8451 (LM-13) - GENOVA 6 cfu anno 1 CHIMICA E TECNOLOGIA FARMACEUTICHE 11674 (LM-13.) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR CHIM/02 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester PREREQUISITES Propedeuticità in ingresso Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami: Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) GENERAL AND INORGANIC CHEMISTRY (PCT)(MD) 55401 2022 MATHEMATICS (PCT)(MD) 55402 2022 PHYSICS (PCT)(MD) 55404 2022 PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY 11674 (coorte 2023/2024) GENERAL AND INORGANIC CHEMISTRY (PCT) 111615 2023 Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) INSTRUMENTAL ANALYSIS OF DRUGS (WITH PRACTICE) 80452 Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) PHYSICS METHODS IN ORGANIC CHEMISTRY (MD) 64193 Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) APPLIED MEDICINAL CHEMISTRY (MD) 67617 Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) PHARMACEUTICAL TECHNOLOGY AND LAW II (WITH PRACTICE9 (PCT MD) 67615 Pharmaceutical chemistry and technology 8451 (coorte 2022/2023) PHARMACEUTICAL TECHNOLOGY AND LAW I (PCT) 67569 TEACHING MATERIALS AULAWEB OVERVIEW The course presents some of the most important topics of physical chemistry: quantum mechanics, classical thermodynamics and chemical kinetics. It consists in 8 CFU and it is intended to the students of the second year of the CTF degree course. AIMS AND CONTENT LEARNING OUTCOMES This is a fundamental course held in the first semester of the second year. Basic concepts of thermodynamics, chemical equilibria, chemical kinetics and theoretical chemistry are provided, in order to make the student critically understand principles of physical chemistry and its applications to chemical, biological, pharmaceutical systems. AIMS AND LEARNING OUTCOMES The course aims at providing basic concepts of physical chemistry, and the critical skills necessary to face general physical-chemical topics from a chemical viewpoint, with particular reference to classical thermodynamics and chemical kinetics. PREREQUISITES The following basic knowledge are required: Basic concepts of mathematics (properties of powers, fundamental integrals, derivatives) Basic concepts of physics (work and energy; basic concepts of electrostatics) Basic concepts of general chemistry. TEACHING METHODS The course consists in 64 hours of mainly frontal teaching; during these lessons the theory is explained and discussed, and examples are shown. During the course, students (divided into groups of 2-3) will be asked to build a glossary in Aulaweb by providing definitions of the key concepts treated during lessons. The key concepts assigned to each group will be used to prepare a presentation for the “Giornata dei Referenti” (see sections “Exam description” and “Assessment methods”). Slides shown during the lessons will be uploaded in Aulaweb and will be available to the student. SYLLABUS/CONTENT - General aspects of theoretical chemistry; the Schroedinger equation, atomic orbitals, the periodic table. - The chemical bond. - Ideal and real gases. - Classical thermodynamics: first, second and third law of thermodynamics; internal energy, enthalpy, entropy, free energy; reversibility and irreversibility. Chemical equilibrium. - Ideal solutions, ideal diluted solutions, real, regular, electrolytic solutions. - General aspects of molecular spectroscopy and photochemistry. - Chemical kinetics. - Dynamics of reaction: theory of collisions and activated-complex theory. - Enzymatic catalysis. RECOMMENDED READING/BIBLIOGRAPHY All the slides used during the lessons will be available in Aulaweb starting from the day of the lesson. In general, notes taken during lessons and the material uploaded in Aulaweb are sufficient for the exam preparation. Nevertheless, the consultation of chemical physics textbooks are recommended to study in depth. Some titles follow: "Physical Chemistry", P.W. Atkins "Physical chemistry", R. Chang TEACHERS AND EXAM BOARD CRISTINA ARTINI Ricevimento: Always, by appointment. Exam Board CRISTINA ARTINI (President) CLAUDIO CANALE MASSIMO DOMENICO OTTONELLI (Substitute) MARCELLA PANI (Substitute) MARINA RUI (Substitute) LESSONS Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The exam consists in the discussion of an oral presentation and in an oral examination. The presentation will be prepared and discussed after the end of the course during an event called “Giornata dei Referenti”. Students will be given several keywords related to topics treated during the course, and they will be asked to build around them a detailed study. Skills will be ascertained through an oral examination, aiming at verifying the comprehension of the topics and the ability to express them by an adequate terminology. ASSESSMENT METHODS During the “Giornata dei Referenti” it will be evaluated the ability of the student to re-elaborate concepts treated during the lessons, as well as his/her ability to build an effective presentation and to discuss it clearly and precisely. The oral examination will focus on the topics treated during the lessons, and it will aim at evaluating whether the student reached adequate skills, as well as whether he/she is able to connect concepts and to critically analyze chemical-physical problems. The exam will consist in questions about the whole programme; it will be important to show the ability to use and critically discuss the topics of the course, as well as to employ an adequate terminology. Exam schedule Data appello Orario Luogo Degree type Note 05/04/2024 09:00 GENOVA Orale 21/06/2024 09:00 GENOVA Orale 08/07/2024 09:00 GENOVA Orale 22/07/2024 09:00 GENOVA Orale 11/09/2024 09:00 GENOVA Orale 23/01/2025 09:00 GENOVA Orale 17/02/2025 09:00 GENOVA Orale