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CODE 34001
ACADEMIC YEAR 2023/2024
CREDITS
SCIENTIFIC DISCIPLINARY SECTOR CHIM/06
LANGUAGE Italian
TEACHING LOCATION
  • GENOVA
SEMESTER 2° Semester
PREREQUISITES
Propedeuticità in ingresso
Per sostenere l'esame di questo insegnamento è necessario aver sostenuto i seguenti esami:
TEACHING MATERIALS AULAWEB

AIMS AND CONTENT

LEARNING OUTCOMES

To give a general idea of various aspects where organic chemistry is connected with biology. In  particular: structure functioning of proteins (enzymes, receptors, channels) and oligosaccharides, and their interaction with potential drugs.

AIMS AND LEARNING OUTCOMES

Aims

The students will be guided to approximately understand the issues associated with drug discovery and with the study of èprpteins and nucleic acids.

TEACHING METHODS

Traditional lessons in the classroom (32 hours). The attendance is not compulsory but, for statistical means, it wil be anyway monitored.

SYLLABUS/CONTENT

Protein: secondary, tertiary and quaternary structure Enzymes: kynetics, catalysis mechanism, examples, classification . Nucleic acids: structure, RNA function. Determination of primary structure. PCR. Topoisomers. Genetic mutations. Principle of drug discovery: Enzyme inhibitors, receptors, ion channels. Glycochemistry. Applications in the fields of antiviral, antitumor drugs, antibiotics, antiinflammatory drugs, anti-asthma drugs, drugs for cardiovascular diseases and so on.

RECOMMENDED READING/BIBLIOGRAPHY

  • Silverman, R.B., "The Organic Chemistry of Drug Design and Drug Action", Academic Press
  • Corey, E.J., Czakó, B. Kürti, L., "Molecules and Medicines", Wiley

TEACHERS AND EXAM BOARD

Exam Board

LISA MONI (President)

ANDREA BASSO

LUCA BANFI (President Substitute)

CHIARA LAMBRUSCHINI (Substitute)

LESSONS

LESSONS START

March 4, 2024

Class schedule

L'orario di tutti gli insegnamenti è consultabile all'indirizzo EasyAcademy.

EXAMS

EXAM DESCRIPTION

The exam will be oral. Only the subjects treated during the lessons (as reported in the slides deposited in aulaweb) will be object of the exam. Students must register to the exam at least 48 hours in advance on https://servizionline.unige.it/studenti/esami/prenotazione

ASSESSMENT METHODS

The oral exam is always carried out by the two teachers and will last at least 30 minutes. In this way, the commission is definitely able to verify with high accuracy if the student has reached or not the learning outcomes.

During the oral exam the student must demonstrate to have reached the learning outcomes, both orally and (most importantly) writing formulas, chemical equations, mechanisms.

When the commission will judge that the learning oucomes have not been reached, the students will be invited to repeat the exam in one of the subsequent dates.

Exam schedule

Data Ora Luogo Degree type Note
24/01/2024 15:00 GENOVA Orale
21/02/2024 15:00 GENOVA Orale
22/05/2024 15:00 GENOVA Orale
26/06/2024 15:00 GENOVA Orale
17/07/2024 15:00 GENOVA Orale
11/09/2024 15:00 GENOVA Orale
02/10/2024 15:00 GENOVA Orale

Agenda 2030 - Sustainable Development Goals

Agenda 2030 - Sustainable Development Goals
Good health and well being
Good health and well being