CODE 67112 ACADEMIC YEAR 2023/2024 CREDITS 2 cfu anno 3 8744 (L-22) - SAVONA SCIENTIFIC DISCIPLINARY SECTOR BIO/14 LANGUAGE Italian TEACHING LOCATION SAVONA SEMESTER 2° Semester MODULES Questo insegnamento è un modulo di: MEDICAL SCIENCE IN SPORTS TEACHING MATERIALS AULAWEB AIMS AND CONTENT AIMS AND LEARNING OUTCOMES This course of pharmacology is designed to form qualified personnel (gymnastic teachers, athletic trainers, experts of rehabilitation....etc), capable to dispense physical activity recognizing the most relevant features (indications and contraindications, side effects...etc) of pharmacologic therapies for those pathologies that are most commonly associated with sports activity. To this aim, the first part of the course examines the dinamics of interaction of drugs with human body, and the mechanisms through which drugs induces therapeutic modification of the diseases. The second part of the course is aimed to examine the most important drug cathegories that can be used in sport population, focusing on those that target sports-related pathologies. The course will detail the pharmacologincal control of inflammation and pain, and the treatment of respiratory tract diseases. Last but not least, the course examines those drugs that, beyond their therapeutic usefulness, are abused in the absence of therapeutic needs, with the purpose of alterate physical performances of athletes. Such unnecessary and often overdosing treatments, expose athletes at high risk to suffer significant side effects or develop late-onset diseases that can severely endanger their health in post-agonistic life. TEACHING METHODS The teaching of pharmacology will be held at unige campus in savona as front lessons. During lessons, the comprehension of the addressed topics will be helped by ppt slideshows. Importantly, slideshow content cannot be considered exhaustive of the topics and the presence in the class is mandatory SYLLABUS/CONTENT Overview on pharmacology Definition of drug, aims of pharmacological therapy, interactions between drugs and body, clinical trials Farmacokinetics Absorption, distribution, metabolism and excretion of drugs. Parameters of pharmacokinetics (bioavailability, distribution volume, clearance, half-life) Farmacodynamics: Targets and mechanisms of action of drugs Agonism and antagonism Side reactions. Pharmacology for cathegories Miorelaxants Antinflammatory drugs (non steoidal antinflammatory drugs, antinflammatory steroids) Analgesic drugs (opiates, paracetamol, adiuvants) Pharmacology of autonomous nerve system (use of agonists and antagonists of sympathetic and parasympathetic systems) Drugs used for pathologies of respiratoty system (Asthma, BCPO, allergic rinithys) Drug abuse in sports doping (anabolic hormones, stimulants, narcotics, diuretics, antinflammatory steroids) RECOMMENDED READING/BIBLIOGRAPHY The text which is best recommended to integrate the topics that have been addressed in lectures is the following: "Lippincott's illustrated reviews: Pharmacology", Authors: Michelle A. Clark, Richard Finkel, Jose A. Rey, Karen Whalen. EDS. Lippincott Williams & Wilkins On unige aulaweb the slides that have been used for the lessons will be available as PDF files TEACHERS AND EXAM BOARD STEFANO THELLUNG DE COURTELARY Ricevimento: Meetings will students will be held at ex inst. of Pharmacology Viale Benedetto XV, 2. Genova, ground floor Phone +39 0103538884. . email: stefano.thellung@unige.it . Exam Board SERGIO AGOSTI CRISTIANO NOVELLI ANNA MARIA RICCIO STEFANO THELLUNG DE COURTELARY (President and Coordinator of Integrated Course) MARA BOSCHETTI (President Substitute) LESSONS LESSONS START The lessons will start the first week of march 2024 in the campus of Savona Class schedule PHARMACOLOGY EXAMS EXAM DESCRIPTION Exames will be performed as interviews in the classroom. ASSESSMENT METHODS Student's knowledge of therapeutical indication and side effects of the most common sport-related drugs will be evaluated. Particular importance will be given to over-the-counter drugs whose use must take into consideration athletes physiology-pahtology characters (age, gender, concomitant drug therapies and personal or familiar disease hystory). FURTHER INFORMATION Student's ability to acknowledge pharmacodynamic interactions of drugs with metabolic, hormonal, and neurotransmettitorial balance in patients indicates their development of a proper attitude toward the use of drugs in sport-related pathologies and is worth of maximal evaluation. Agenda 2030 - Sustainable Development Goals Good health and well being Quality education