CODE 57736 ACADEMIC YEAR 2024/2025 CREDITS 3 cfu anno 1 SCIENZE MOTORIE, SPORT E SALUTE 8744 (L-22) - SAVONA SCIENTIFIC DISCIPLINARY SECTOR BIO/13 TEACHING LOCATION SAVONA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: GENERAL BIOLOGY AND PROPEDEUTICS BIOCHEMISTRY TEACHING MATERIALS AULAWEB OVERVIEW This Applied Biology module is part of the General Biology and Preparatory Biochemistry class and it covers 30 hours lecturing of basic biology and genetics for a total of 3 CFU. AIMS AND CONTENT LEARNING OUTCOMES The Applied Biology program will cover the main topics in Biology and Genetics which students will nedd to further understand the academic course in Physical Education Science. AIMS AND LEARNING OUTCOMES This class will help students to develop knowledge, understanding and a strong foundation in cell biology and the basics in genetics. By attending class and by studying on their own, students will be able to: understand how animal cells are structurally and functionally organized; learn inter-cellular communication principles and physiological interactions between cells and their extracellular environment; understand cell metabolism and cell replication versus reproduction; acquire knowledge on how cell genetic information is inherited, expressed and modulated; develop specific know-how, while improving their learning and communication skills along with thei capacity of critical analysis. This class will allow students to fully develop strong understanding of the basics in biology and genetics. This will help them to build strong foundation to further expand their knowledge on the main relevant physiological and pathological processes in physical activity and professional sport performance. TEACHING METHODS Students are required to attend class for at least 75% of the scheduled lessons. The module will include 30 hours of lecturing; each lecture will take place weekly and will last 4 hours (but for the first one, as set of about 2 hours for introduction of the module). Class will be managed as frontal lectures with Power Point notes. Basics in cell biology and genetics will be addressed during class by means of active discussion engaged by the Lecturer via examples and specific practice exercise. Students will have to go through the main topics explained at class and be able to solve genetic quiz. Students can take advantage of online material (lectures power point notes) available on the AulaWeb website; Lecturer can be reached via email to arrange specific 1-to-1 meeting for further assistance/explanation as needed. In case of certification of specific learning disability, disability or other special educational needs, please contact both the Department contact person, Prof. Nicola Girtler, and the lecturer at the beginning of the lectures to agree on teaching and exam methods which, in compliance of the teaching objectives, take into account individual learning methods and provide suitable compensatory/dispensatory tools recognized by the University SLD Student Service. SYLLABUS/CONTENT This module will address the following main topics: Introduction. Molecular and functional role of proteins, carbohydrates, lipids and nucleic acids. Origin of life and cells. The cell theory. Prokariotic and Eukariotic cell structure. Extracellular structure and matrix. Cell membrane: structure, functional roles and trans-membrane transport. Intercellular communication, common signal transduction pathways. ATP as master key of energy transfer; enzyme stucture and functional definition. Cell metabolism: glucose oxidation; aereobic and anaerobic glucose catabolism. Cell cycle and cell proliferation. Mitosis. Meiosis. Apoptosis and necrosis. Introduction to cancer cells. Modern genetics: the Mendel's laws. Functional role of allels, genes, chromosomes. Different patterns of transmission of inherited genetic traits. Functional role of DNA: chemical structure, replication and repair mechanisms. From DNA to proteins: DNA transcription into mRNA and transduction of the genetic information into a complete polypeptide. The genetic code. Genetic mutations and molecular medicine. Regulation of genetic expression in viruses, prokariotic and eukariotic cells; alternative splicing. RECOMMENDED READING/BIBLIOGRAPHY Power point notes of class lectures are available for students to be downloaded from AulaWeb. Files are strictly for personal use only; files must not be shared on social media, posted on any internet website or put on any sharing platform; files must not be printed out for sale or photocopied. The following textbook can be also taken in consideration as reference, but it does not replace frontal lectures: Sadava, Hillis, Heller, Berenbaum. Life, The Science Of Biology ( 9th Ed.) The Italian version is: Sadava, Hillis, Heller, Berenbaum. Elementi di biologia e genetica. Quarta Edizione italiana condotta sulle decima edizione americana. Zanichelli. Extra information can be found on: www.online.universita.zanichelli.it/sadava-4e Other basic biology and genetics textbooks can be also used, providing they are intended for University Master Degree courses. TEACHERS AND EXAM BOARD CHIARA GENTILI Ricevimento: By appointment by email: chiara.gentili@unige.it LESSONS LESSONS START I semester Class schedule APPLIED BIOLOGY EXAMS EXAM DESCRIPTION Exam assesment is intended as a one-to-one oral interview with the Lecturer. There will be 7 exams per year: 3 during the winter session (January and February) and 4 during the summer session (3 in June-July and one in September). Extraordinary dates will NOT be arranged. Online registration with at least 48h advance is mandatory to have access to the exam Both Biology and Biochemistry exams must be succesfully completed by the end of the same session so to compute the final mark (calculated as mean of the two parts). Otherwise either the Biology or Biochemistry mark will not be considered and will have to be assessed again. ASSESSMENT METHODS Details about final exam will be explaind during class. Assesment will be performed via a 1-to-1 discussion about the main topics illustrated during class. Students will be assessed considering their knowledge and understanding on the main topics illustrated during class. Their communicative and making judjements skills will be evaluated as well. Students will be asked to solve genetics quiz and practical questions. FURTHER INFORMATION For clarifications, further explanation or any required information, students are strongly invited to contact the Lecturer, Prof. Bollini, in advance by email at: sveva.bollini@unige.it