CODE 67403 ACADEMIC YEAR 2024/2025 CREDITS 3 cfu anno 4 MEDICINA E CHIRURGIA 8745 (LM-41) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR MED/17 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY TEACHING MATERIALS AULAWEB OVERVIEW Systematic knowledge of the most important Infectious Diseases. Ability to integrate anamnestic data, symptoms, objective signs and functional alterations of each Infectious Disease with the diagnostic, instrumental, laboratory and therapy path. Know the fundamentals inherent in chemoprophylaxis and the therapy of the most important Infectious and Tropical Pathologies. Reasoning on the infectious disease patient through a differential diagnosis approach with respect to other pathologies. AIMS AND CONTENT AIMS AND LEARNING OUTCOMES • Infectious Diseases will be taught from the perspective of both organ localization (pneumonia, meningitis, bacteremia, etc.) and etiology. • The recognition of clinical presentations of infectious diseases and septic syndromes will be dealt with extensively, leading students and young doctors to recognize emergencies in Infectious Diseases (sepsis, meningitis) and to follow a reasoned diagnostic algorithm • The Integrated Course will include both lectures and presentation of clinical cases • Particular attention will be paid to the appropriate use of antimicrobials (antimicrobial stewardship) and the risk of development of antimicrobial resistance • Other important topics include Emerging Infectious Diseases, Sexually Transmitted Diseases and HIV infection TEACHING METHODS Frontal lessons Visit to the Infectious Diseases clinic or other consulting departments with specific insights on the infectious disease patient Seminars (active participation of students is essential) Group work The teaching will cover 60 hours of frontal lessons (30 infectious diseases, 30 microbiology) on all arguments included in the program and additional 50 hours (2 CFU) of practical exercises (apprenticeship) in infectious diseases. Practical activities will be carried out at the Infectious Diseases Clinic of the University of Genoa. During practical activities the students will discuss clinical cases with Infectious Diseases specialists. Goals of the training: To acquire knowledge on microbiologic diagnosis of infections. To acquire knowledge of appropriate microbiological procedures, with particular attention to the appropriateness of tests and to result interpretations For students with valid certifications for Specific Learning Disorders (SLD): Examination modalities -> the Student may take the Clinical Microbiology part and the Infectious Diseases part on separate days, normally consecutive. In any case, the Coordinator may evaluate different modes in agreement with the Student SYLLABUS/CONTENT Infectious Diseases programme: General infectious diseases, appropriate use of antibiotics HIV infection Sexually transmitted infections Defense mechanisms against infectious diseases Herpesvirus infectious diseases Pneumonia and meningitis Gastroenteritis Viral hepatitis Abdominal infections Genitourinary infections Skin and soft tissue infections Malaria and other tropical diseases Endocarditis Tuberculosis Opportunistic infections in the course of HIV-AIDS Infections in the newborn Biological drug-related infections Infections in the immunosuppressed patient Infections in pregnancy Emerging infections: Ebola, Zika, Dengue, etc ... Hospital infections Sepsis and septic shock Fungal infections and infectious rash Parasitosis Antimicrobial stewardship: antibiotic use and resistance, opportunistic infections Fungal infections and infectious exanthems. Endemic infections (Lyme, WN, TBE, Lepto). The COVID today RECOMMENDED READING/BIBLIOGRAPHY M. Moroni, R. Esposito, S Antinori: Malattie Infettive, ottava edizione. Elsevier Masson Mandell, Douglas & Bennet- Principles and Practice of Infectious Diseases, 9 Edition 2019 in-depth book: M. Bassetti: Chemioterapici antinfettivi e loro impiego razionale 9° ed, 2012 Academy Srl M. Bassetti: Terapia e profilassi delle infezioni, III Ed. 2022 Medizioni Srl TEACHERS AND EXAM BOARD ANDREA DE MARIA MALGORZATA KAROLINA MIKULSKA ANTONIO DI BIAGIO Ricevimento: Appointment via e_mail: antonio.dibiagio@unige.it MATTEO BASSETTI Ricevimento: Students can arrange an appointment by e-mail: matteo.bassetti@unige.it ANTONIO VENA DANIELE ROBERTO GIACOBBE Ricevimento: By appointment. Mail: danieleroberto.giacobbe@unige.it Exam Board ANDREA DE MARIA (President) MALGORZATA KAROLINA MIKULSKA (President) ANTONIO DI BIAGIO DANIELE ROBERTO GIACOBBE ANNA MARCHESE ANTONIO VENA MATTEO BASSETTI (President and Coordinator of Integrated Course) LESSONS LESSONS START 29 sept 2020 presentation of the course Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral examination (according to calendar available on the dedicated website) ASSESSMENT METHODS Learning will be assessed only by means of the final oral examination . All students will be required to obtain a minimun score of 18/30. To obtain this result, students must demonstrate to have acquired: -knowledge on clinical presentation, diagnosis and prophylaxis, together with therapeutic approach to the main infectious diseases. -skills on differential diagnosis and rational use of laboratory tests and imaging resources -skills on principles of antimicrobial treatment -skills on the appropriate use of antibiotic treatment and on the impact of the inappropriate antibiotic prescription on the emergence of antibiotic resistance The final score will be determined by: -ability to face in a critical manner to all the arguments discussed during the examination -quality of exposure -use of an appropriate vocabulary The maximum score (30/30 lode) will be given in case of excellence. FURTHER INFORMATION Students can arrange an appointment with teachers by e-mail Prof. Matteo Bassetti: matteo.bassetti@unige.it Prof. Andrea De Maria: de-maria@unige.it Prof.ssa Malgorzata Mikulska: m.mikulska@unige.it Prof. Antonio Di Biagio: antonio.dibiagio@unige.it Prof. Antonio Vena: antonio.vena@unige.it Prof. Daniele Roberto Giacobbe: daniele.roberto.giacobbe@unige.it