CODE 80448 ACADEMIC YEAR 2024/2025 CREDITS 5 cfu anno 3 CHIMICA E TECNOLOGIA FARMACEUTICHE 8451 (LM-13) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/15 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: PLANT BIOLOGY AND BIOACTIVE COMPOUNDS (I.C.)(PCT MD) TEACHING MATERIALS AULAWEB AIMS AND CONTENT AIMS AND LEARNING OUTCOMES At the end of the course, the student should know the basics of plant biology, including the topics of cytology, histology and plant physiology described in the programme. The student should be able to explain and compare different ways in which cells and their vital subsystems function under specific conditions and/or in relation to different cell types. The student should also be able to remember and use the appropriate and scientifically correct terminology. It is expected that the student will thus have a competence that will enable him/her to undertake a more detailed analysis of cell homeostasis and metabolism in subsequent courses and to frame the cell as a functional unit susceptible to therapeutic and pharmacological treatment. TEACHING METHODS The course consists of 48 hours of lectures. Lectures may be delivered either face-to-face or remotely -via the University's IT platforms- at the same time as the presentation of slides via PowerPoint-type files. Discussion in the classroom or on dedicated remote channels is strongly encouraged. Some parts of the lecture will also be conducted in interactive mode, thanks to the availability of freely available web resources. Teaching materials are available to students on the AulaWeb site, via controlled access. Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department ( Prof. Luca Raiteri, Luca.Raiteri@unige.it ) before class begins, in order to liaise and arrange the specific learning methods and ensure proper achievement of the learning aims and outcomes. VERY IMPORTANT: any request for compensatory tools and adaptations in the exam MUST be done within 10 working days before the date of the exam according to the instructions that can be found at https://unige.it/disabilita-dsa/comunicazioni SYLLABUS/CONTENT The origins of plant life EUKARYOTIC CELLS EVOLUTION OF TERRESTRIAL PLANTS: Phylogeny. Position of sporangia. Groups main groups: algae, bryophytes, lycophytes. SEED PLANTS (SPERMATOPHYTES): dominance of the sporophytic generation. THE ANGIOSPERMS: eudicotyledons. The genomes THE NUCLEAR GENOME: THE CHROMOSOMES THE CHROMOSOMIC DNA: repeated sequences, transposons. THE REGULATION OF NUCLEAR GENES: regulatory sequences, transcription factors, epigenetic modifications, GENOME SEQUENCES: The Arabidopsis genome, plant genome duplications. CITOPLASMATIC GENOMES: endosymbiosis, plastidial DNA replication, processes post-transcriptional regulation of plastidial gene expression, exchanges between plastids and the nucleus. Plant cells THE CELL CYCLE: transition from one phase of the cell cycle to the next, molecular controls of the cell cycle, endoreduplication. CELL DIVISION: meiosis, the role of the cytoskeleton in mitosis, formation the phragmoplast, vesicular transport THE ORGANULES: biogenesis of plastids and mitochondria, endomembrane system, vacuole. THE PRIMARY CELL WALL: wall constituents, cellulose synthesis, plasmodesmata. DISTENSION AND SHAPE OF THE CELL: properties of the plasma membrane, proton transport, movement of water across the plasma membrane, functionality of the vacuole, the direction of cell distension. SECONDARY AND CUTICAL WALL: structure and components of the secondary wall, lignin, the cuticle. Tissues MERISTEMATIC TISSUES PARENCHIMATIC TISSUES: the photosynthesis parenchyma, the secretion parenchyma, the aeriferous parenchyma, the transport parenchyma, the reserve parenchyma. TEGUMENTAL TISSUES: the epidermis, rhizodermis, endodermis, exodermis, peridermis. peridermis. CONDUCTING TISSUES: xylem: properties and formation of conduction elements. conduction. Phloem. MECHANICAL TISSUES: collenchyma, sclerenchyma. SECRETORY TISSUES: secretory idioblasts, pockets and secretory channels. Metabolism CARBON ASSIMILATION: PHOTOSYNTHESIS: light-capturing processes on the tilacoids of the chloroplast, the chlorophyll, reaction centres, photosystems, the Calvin cycle. PHOTORESPIRATION: modes of control of Rubisco, C4 plants. THE TRANSPORT OF SUCAROSE: movement of sucrose the loading of the phloem. THE ACCUMULATION OF CARBON THE MOVEMENT OF WATER AND MINERALS: hydraulic transport mechanism, the movement of mineral nutrients. The development THE DEVELOPMENT OF THE HEMBRION AND SEED: endosperm, embryo, tegument. DEVELOPMENT OF THE ROOT: successive stages of differentiation, development of lateral roots, external organisation of the primary root. lateral roots, external organisation of the primary root, internal organisation of the root, organisation of the primary meristem zone and the cuff, the zone of determination, zone of differentiation, secondary structure. THE DEVELOPMENT OF THE STEM: meristematic stem apex, leaf buds the shape of the leaves the leaf senescence, internal anatomical organisation of the primary structure of the stem, the secondary structure of the stem FROM VEGETATION TO REPRODUCTIVE DEVELOPMENT. meristems of the flower and inflorescence, development of flower organs. FROM THE SPOROPHYTE TO THE GAMETOPHYTE: the pollen granule, the ovule, growth of the pollen tube pollen, self-incompatibility, fertilisation. RECOMMENDED READING/BIBLIOGRAPHY Recommended text: Smith, Coupland, Dolan, Harberd, Jones, Martin, Sablowski, Amey. Plant Biology. Italian edition edited by Donato Chiatante 2011. Zanichelli Publisher. TEACHERS AND EXAM BOARD PAOLO GIORDANI Ricevimento: The lecturer -Prof. P. Giordani- receives students by appointment to be arranged by contacting the lecturer by e-mail (paolo.giordani@unige.it), at the Sturla seat of DIFAR, viale Cembrano, 4 Genova. If necessary, the lecturer can also receive students by remote connection. Exam Board ANGELA BISIO (President) GUENDALINA OLIVERO PAOLO GIORDANI (President Substitute) LESSONS LESSONS START Lessons will begin as per the calendar and timetable prepared by the competent Teaching Secretariat. Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Oral examination on the topics described in the programme ASSESSMENT METHODS During the oral examination, the student will be asked questions of increasing complexity; on the basis of the answers, competence in the subject matter will be deepened; language property, use of appropriate terminology and correlation skills will also be assessed. Exam schedule Data appello Orario Luogo Degree type Note 17/04/2025 09:00 GENOVA Scritto + Orale 16/06/2025 09:00 GENOVA Scritto + Orale 04/07/2025 09:00 GENOVA Scritto + Orale 21/07/2025 09:00 GENOVA Scritto + Orale 01/09/2025 09:00 GENOVA Scritto + Orale 19/09/2025 09:00 GENOVA Scritto + Orale 19/01/2026 09:00 GENOVA Scritto + Orale 02/02/2026 09:00 GENOVA Scritto + Orale