CODE 111101 ACADEMIC YEAR 2024/2025 CREDITS 1 cfu anno 1 TECNICHE DELLA PREVENZIONE NELL'AMBIENTE E NEI LUOGH 9298 (L/SNT4) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/14 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester MODULES Questo insegnamento è un modulo di: GENERAL PATHOLOGY AND TOXICOLOGY TEACHING MATERIALS AULAWEB AIMS AND CONTENT AIMS AND LEARNING OUTCOMES The teaching of general pharmacology is composed by two sections. The first is aimed to introduce students into the basic knowledge of the interaction between drugs and human body and its therapeutical outcomes. In particular, the teaching will focus on the capacity of the body to react to the treatment, inducing the metabolism and, ultimately the elimination of the drug. On the other hand the drug induce a physiological or structural in the body that can favor the mitigation of potentially severe symptoms of a pathology, thus helping the healing. In details, the following objectives will be pursued by the teaching. -The pharmacokinetics behavior of drugs (how is absorbed, distributed, metabolized and eliminated by the body) -The pharmacodynamic of drugs (their mechanisms of action) -Their clinical significance (indications, contraindications, tolerance, intolerance and side effects) The second part of the course is aimed to describe some pharmacological strategies that still represents first choice procedures in clinical emergencies; among these particular relevance will be given to the pharmacological modulation of autonomic nerve system and the control of inflammation and allergy by non steroidal antinflammatory drugs and glucocorticoids. TEACHING METHODS Teaching of general pharmacology wil be held as front lessons. Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department before class begins, in order to arrange the specific teaching methods and ensure proper achievement of the learning aims and outcomes. SYLLABUS/CONTENT General pharmacology: Introduction to pharmacological and clinical characteristics of drugs Pharmacokinetic: absorption, distribution, metabolism and elimination of drugs Pharmacodynamic: molecular, cellular and tissutal targets of drugs, agonism and antagonism, tolerance and intolerance to drugs, side effects Clinical pharmacology: Pharmacology of autonomic nervous system, agonists and antagonists on sympathetic and parasympathetic system . Non steroidal antinflammatory drugs; glucocorticoids. RECOMMENDED READING/BIBLIOGRAPHY PDF files containing the slides that have been used during the course will be availabte in the aulaweb section of unige website TEACHERS AND EXAM BOARD STEFANO THELLUNG DE COURTELARY Ricevimento: Meetings will students will be held at ex inst. of Pharmacology Viale Benedetto XV, 2. Genova, ground floor Phone +39 0103538884. . email: stefano.thellung@unige.it . Exam Board MARIAPAOLA NITTI (President) PAOLA MODESTO STEFANO THELLUNG DE COURTELARY VINCENZO TROVATO CINZIA MARIA DOMENICOTTI (President and Coordinator of Integrated Course) LESSONS LESSONS START Lessons will start on march Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION The exam will be performed in form of a talk ASSESSMENT METHODS Students will be asked to reckon the interaction between drugs and the human body and the physiological modifications that can be produced. The ability to discuss of the subjective and objective variable that can interfere with the therapeutic acticvity of drugs will be regarded as a plus in the evaluation on the exam FURTHER INFORMATION To pass the course of patologia generale e tossicologia, students must pass all the sections that compose it whithin the same semester.