The course aims to impart knowledge on the structure and complexity of the eukaryotic genome, its structural and functional organization. Additionally, it seeks to clarify the mechanisms responsible for genome stability, such as replication accuracy and DNA repair mechanisms. Special emphasis is placed on the regulation of gene expression in both bacteria and eukaryotes. Finally, the module provides an overview of molecular biology techniques relevant to the production of biotechnological drugs. The course is conducted interactively, aiming to engage students in theoretical experiments and encourage them to develop hypotheses and potential experimental strategies to test them.
Lectures are organized to actively engage participants in problem-solving activities, aimed at applying the knowledge acquired.
Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department ( Prof. Luca Raiteri, Luca.Raiteri@unige.it ) before class begins, in order to liaise and arrange the specific learning methods and ensure proper achievement of the learning aims and outcomes. VERY IMPORTANT: any request for compensatory tools and adaptations in the exam MUST be done within 10 working days before the date of the exam according to the instructions that can be found at https://unige.it/disabilita-dsa/comunicazioni
The 24-hour module is an intensive course aimed at providing, in three CFU (Crediti Formativi Universitari), fundamental knowledge of contemporary Molecular Biology and an overview of new techniques relevant to the production of biotechnological drugs. Specifically, the topics covered will be:
Bruce Alberts et al. L'essenziale di biologia molecolare della cellula (5° edizione)
Bruce Alberts et al. Biologia molecolare della cellula (6° edizione)
Watson J. Biologia molecolare del gene (8° edizione)
Ricevimento: Tuesday at 12:00 PM at CBA A3, Room 31. Students wishing to attend must book by email (paolo.malatesta@unige.it) at least one day in advance.
MASSIMO GRILLI (President)
CHIARA CERVETTO
ERNESTO FEDELE (Substitute)
MARCO MILANESE (Substitute)
GUENDALINA OLIVERO (Substitute)
ANNA MARIA PITTALUGA (Substitute)
LUCA RAITERI (Substitute)
CAROLA TORAZZA (Substitute)
Oral Exam (about 30/40 minutes)
The exam for the Molecular Biology module is designed to assess not only students' ability to memorize and repeat information, but primarily their capacity to apply acquired knowledge critically and constructively. Questions will encompass the entire course curriculum, focusing on the ability to organize answers logically and coherently, and to effectively apply learned knowledge to solve new problems. Emphasis will be placed on critical analysis, depth of individual study, mastery of concepts, and the ability to connect them to other knowledge gained throughout the course.