OVERVIEW

The "Analysis of drugs II" course is aimed at third year students of the Single Cycle Master's Degree Course in Pharmaceutical Chemistry and Technology (CTF). It aims to introduce students to the qualitative analysis of inorganic and organic substances of pharmaceutical interest. The course allows the acquirement of 8 credits and consists of theoretical lessons and practical exercises in the laboratory.

AIMS AND CONTENT

LEARNING OUTCOMES

The course is structured into lectures and laboratory exercises. The objective of the lectures is to deepen the understanding of safety regulations, laboratory practices, and qualitative analysis procedures for substances of pharmaceutical interest. In particular, experimental protocols will be illustrated for the qualitative identification of a) inorganic drugs and any impurities present in them, and b) organic drugs based on the elements and functional groups present. Methodologies for determining the physicochemical properties of the compounds under analysis will also be covered. Students are expected to demonstrate their ability to apply the acquired knowledge through the identification of unknown substances during individual laboratory exercises.

AIMS AND LEARNING OUTCOMES

The student will develop the ability to plan and execute qualitative analysis and characterization procedures for identifying drugs or compounds of pharmaceutical interest, encompassing both inorganic and organic substances.

PREREQUISITES

The student must have adequate knowledge of general and inorganic chemistry, as well as organic chemistry

TEACHING METHODS

The teacher will hold the lectures in the classroom with the help of slides that will be made available to students. Exercises will be introduced by a short illustrative lesson that will be held in the classroom and/or in the laboratory. The exercises will be individual. Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department (Prof. Luca Raiteri, Luca.Raiteri@unige.it ) before class begins, in order to liaise and arrange the specific learning methods and ensure proper achievement of the learning aims and outcomes. VERY IMPORTANT: any request for compensatory tools and adaptations in the exam MUST be done within 10 working days before the date of the exam according to the instructions that can be found at https://unige.it/disabilita-dsa/comunicazioni

SYLLABUS/CONTENT

The course of 8 CFU (96 hrs of commitment in frontal teaching activity per student) is divided into two parts: a theoretical one, consisting of 40 hours of lessons, and a practical one, which includes 56 hours of individual exercises in the laboratory. The practical exercises performed in the laboratory are carried out in close correlation with the topics of the course, as indicated in the following program.

Syllabus: Chemistry Laboratory Safety Rules. Laboratory risk prevention. Inorganic qualitative analysis for the characterization of inorganic drugs and associated impurities. Assay in bunsen flame and in crucible. Systematic search for the anions of groups I, II, III and IV. Systematic search for cations of groups I, II, II, IV, V and VI. Organic qualitative analysis based on the research of the elements and on the identification of functional groups present in compounds of pharmaceutical interest. Preliminary tests: organoleptic test, combustion test, organic elemental analysis, solubility, identification tests. Functional group analysis. Determination of some physical constants.

RECOMMENDED READING/BIBLIOGRAPHY

• F. Savelli, O. Bruno, Analisi chimico farmaceutica – Ed. Piccin
• V. Cavrini, V. Andrisano, Principi di analisi farmaceutica – Ed. Esculapio
• A. Carta, M. G. Mamolo, F. Novelli, S. Piras, “Analisi Farmaceutica Qualitativa”, Ed. EdiSES

TEACHERS AND EXAM BOARD

LESSONS

LESSONS START

Second semester of the academic year 2025/2026. The course schedule can be viewed at the address https://easyacademy.unige.it/portalestudenti/

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The exam will be oral and will focus on the topics developed in the theoretical lessons and in the practical laboratory exercises.

ASSESSMENT METHODS

The assessment will primarily consider the oral exam and, to a lesser extent, the results of the analysis conducted during practical laboratory exercises.

FURTHER INFORMATION

Please contact the teacher for additional information not included in the course description.