OVERVIEW

The "Analysis of drugs II" course is aimed at third year students of the Single Cycle Master's Degree Course in Pharmacy. It aims to introduce the student to the qualitative analysis of inorganic and organic substances of pharmaceutical interest. The various analysis methods are first described at a theoretical level and then put into practice through individual laboratory exercises.

AIMS AND CONTENT

LEARNING OUTCOMES

The course aims to provide students with theoretical notions and practical skills related to the various qualitative analysis methods of substances of pharmaceutical interest, both inorganic (search for elements) and organic (identification of functional groups). In addition, the basic notions of the most common spectroscopic techniques will be provided.

AIMS AND LEARNING OUTCOMES

At the end of the course, the student will have acquired: i) knowledge of the reaction mechanisms underlying chemical tests; ii) knowledge of qualitative analysis procedures for the determination of inorganic and organic substances; iii) ability to critically interpret experimental results; iv) knowledge of the most common spectroscopic techniques

PREREQUISITES

The student must have knowledge of organic and inorganic chemistry

TEACHING METHODS

The teacher will hold lectures in the classroom with the help of slides that will be made available to students. Individual laboratory exercises will be introduced by a short illustration that will be held in the classroom and in the laboratory.

Any Student with documented Specific Learning Disorders (SLD), or with any special needs, shall reach out to the Lecturer(s) and to the dedicated SLD Representative in the Department ( Prof. Luca Raiteri, Luca.Raiteri@unige.it ) before class begins, in order to liaise and arrange the specific learning methods and ensure proper achievement of the learning aims and outcomes. VERY IMPORTANT: any request for compensatory tools and adaptations in the exam MUST be done within 10 working days before the date of the exam according to the instructions that can be found at https://unige.it/disabilita-dsa/comunicazioni

SYLLABUS/CONTENT

Safety and risk prevention rules in a chemical laboratory

Qualitative inorganic analysis: dry and rapid tests; systematic search for anions: phosphates, thiosulfates, iodides, bromides, chlorides, carbonates, acetates, sulphates, nitrates, nitrites; systematic search for cations: silver, barium, bismuth, copper, aluminium, iron, manganese, zinc, calcium, magnesium

Qualitative organic analysis: preliminary tests, behaviour tests and specific tests of: alcohols, polyalcohols, sugars, phenols, carboxylic acids, amines, pyridine and purine derivatives, alkaloids, amino acids, sulphonamides, esters, amides

Spectroscopic methods: notions of UV/VIS, IR, NMR, mass spectrometry

RECOMMENDED READING/BIBLIOGRAPHY

-F. Savelli, O. Bruno, “Analisi Chimico Farmaceutica”, Ed. Piccin

-A. Carta, M. G. Mamolo, F. Novelli, S. Piras, “Analisi Farmaceutica Qualitativa”, Ed. EdiSES

-G. Caliendo, A. Carocci, A. Carta, A. Catalano, A. Corvino, F. Fiorino, F. Frecentese , E. Magli, M.G. Mamolo, E. Perissutti , S. Piras, I. Saccone, V. Santagada, L. Scipione, B. Severino, D. Zampieri, "Manuale di analisi qualitativa", Ed. EdiSES

TEACHERS AND EXAM BOARD

LESSONS

LESSONS START

The timetable for this course can be found at: EasyAcademy Portal

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

The exam consists of an oral test. The oral test focuses on the topics covered both in class and in the laboratory. In particular, the identification of an inorganic substance and an organic substance and the interpretation of the IR and NMR spectra of an organic compound will be required.

ASSESSMENT METHODS

The student must demonstrate knowledge of the structures, mechanisms of action, oxidation-reduction reactions and chemical characteristics of the compounds being analyzed, with particular reference to the properties that can be highlighted through chemical tests. The evaluation will take into account both the oral exam and the results of the unknown tests carried out during the laboratory exercises

FURTHER INFORMATION

Contact the teacher for further information not included in the teaching sheet