AIMS AND CONTENT

LEARNING OUTCOMES

Microorganisms have an extraordinary impact on the entire life and the composition of our planet. Microorganisms and humans have a very close relationship. 
Some thousands of microbial species, collectively known as microbiota, live in our body and plays useful functions, while other species, pathogens, may cause morbidity. Upon the completion of this course the students should know the biology of the microorganisms and their strategies to cause diseases in humans and in particular in oral cavity

AIMS AND LEARNING OUTCOMES

General Microbiology: To know the main characteristics of prokaryotes, eukaryotes and viruses and their classification. The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease).
General Bacteriology: To know the characteristics of bacteria (bacterial structure, growth and microbial metabolism, overview of bacterial genetics). To understand the bacterial pathogenicity and virulence factors (adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antiphagocytic mechanisms). To know the major classes of chemotherapeutic agents and antibiotics  and their main characteristics (spectrum of action, target, pharmacokinetics and mechanisms of drug resistance).

Bacteriology : to know the main characteristics of Stafilococci, Streptococci, Enterococci, Enterobacteriales, Pseudomonas, Mycobacteria, mycoplasma  and legionella  

General Virology: To know the general characteristics of the viruses (structure and composition,  viral classification, viral replication, viral genetics overview). To understand the mechanism of viral penetration into the host,  viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation). To know the antiviral drugs
Virology: : to know the main characteristics of HIV, epatitis virus (HAV, HBV, HCV) and Herpes virus

Mycology a: To know the general characteristics of pathogenic fungi 

Oral Microbiology: to know the characteristics of the oral ecosystem, oral microbiota and the pathogenicity mechanisms causing caries, gingivitis, periodontitis.

TEACHING METHODS

20 hours in classroom

Students who have valid certification of physical or learning disabilities on file with the University and who wish to discuss possible accommodations or other circumstances regarding lectures, coursework and exams, should speak , at the beginning of the course, both with the instructor and with the Department’s disability liaison to agree about individual learning methods

SYLLABUS/CONTENT

-Main characteristics of prokaryotes, eukaryotes and viruses and their classification.
 -The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease)
 - Characteristics of bacteria (bacterial structure, growth and bacterial metabolism, overview of bacterial genetics) .
-Bacterial pathogenicity and virulence factors (input, adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antiphagocytic mechanisms)
-Classification of antibiotics and their spectrum of activity, and mechanisms of drug resistance. - General characteristics of viruses (structure and composition, viral classification, viral replication, viral genetics overview). 
-Mechanism of viral penetration into the host, viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation). Antiviral drugs.

- General characteristics of pathogenic fungi 
-General characteristics of main microbial species causing diseases (Stafilococci, Streptococci, Enterococci, Enterobacteriales, Pseudomonas, Mycobacteria, mycoplasma  and legionella  

HIV, epatitis virus (HAV, HBV, HCV) and Herpes virus)

-Oral Microbiology; oral microbiota, microorganisms causing caries, gengivitis, parodontitis..

RECOMMENDED READING/BIBLIOGRAPHY

Microbiologia: AA.VV. Principi di microbiologia Medica. Casa Editrice Ambrosiana

TEACHERS AND EXAM BOARD

Exam Board

ANNA MARCHESE (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

IGIENE DENTALE 9289 | Orario e calendario accademico | UniGe | Università di Genova | Corsi di Studio UniGe

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

oral exam

ASSESSMENT METHODS

The evaluation is carried out through the only final exam which seeks to ascertain the actual acquisition by the student of the expected learning results. To demonstrate their knowledge, the students will be able to know:
-the main characteristics of prokaryotes, eukaryotes and viruses and their classification. The host-microbe interactions (symbiosis, parasitism, opportunism, colonization, infection, disease); 
-the characteristics of bacteria (bacterial structure, growth and microbial metabolism, overview of bacterial genetics);
-the bacterial pathogenicity and virulence factors (input, adherence to host tissue, invasion, permanence, exotoxins and endotoxins, hydrolytic enzymes, antiphagocytic mechanisms), intracellular parasites and heterogeneity antigen;
-the major classes of chemotherapeutic agents and antibiotics (beta-lactams, glycopeptides, aminoglycosides, tetracyclines, quinolones, chloramphenicol, macrolides, clindamycin, oxazolidinones, streptogramins, nitroimidazoles, rifampin) and their main characteristics (spectrum of action, target, pharmacokinetics and mechanisms of drug resistance); 
-susceptibility and antimicrobial resistance  and quantitative and qualitative determination of antibiotic activity;
-the general characteristics of the viruses (structure and composition,  viral classification, viral replication, viral genetics overview);
-the mechanism of viral penetration into the host,  viral transmission, spreading, tropism, virulence and cytopathic effects, persistence, latency, reactivation);
-the antiviral drugs and resistances;
-the general characteristics of pathogenic fungi.

-the characteristics of the main species of medical interest

-the characteristics of oral ecosystem, oral microbiota and pathogens causing caries, gengivitis, parodontitis..
A minimum mark of 18/30 is required to pass the module. The mark 30/30 with any honors will correspond to an excellent knowledge of all argoments.

FURTHER INFORMATION

Ask the professor for other information not included in the teaching schedule