OVERVIEW

The Integrated Course of Clinical Pathology I and Medical Technical Sciences is the first course of the 1st year which characteriz the profession of Biomedical Laboratory Technician. The students, having followed the lessons common to all the Health Care Professional Studies Courses, will have the first approach on Laboratory Medicine and its basics in the integrated course, in order to have knowledge that will enable them to understand the subjects discussed In the following years of the Course

AIMS AND CONTENT

LEARNING OUTCOMES

Acquire fundamental, basic and specialized knowledge of laboratory medicine and organization, the professional development of TSLB and healthcare legislation. Get in-depth knowledge of: • blood components, primary and secondary hemostasis, coagulation factors, intrinsic and extrinsic pathways • hematology, coagulation, microscopic reading techniques.

AIMS AND LEARNING OUTCOMES

The integrated course is divided into two disciplinary field,

 Clinical Pathology I and Medical Technical Sciences. The section on Clinical Pathology, entrusted to Medical Doctors, deals with subjects of Basic Laboratory Medicine, physiopathology in the human body, primary and secondary coagulation system, hematopoiesis and blood cells, the analytical process of the samples in the Its entirety and the basics of guidelines and EBM for a correct analytical path of the sample. The part related to the Medical Technical Sciences, in line with the subjects covered in the section of Clinical Pathology, is entrusted to Professors belonging to the professional profile of the Biomedical Laboratory Technician, focusing on the analytical techniques, methods and processes of the Hematocatalysis and microscopy, clinical chemistry in the field of urgency, special examinations such as immunosuppressive drugs, emogasanalysis, chains of custody for sexual violence and toxicological examinations, and bases for treating samples in the immune transfusion centers; The following aspects will be analyzed: the evolution of the Laboratory of Analysis, health and university legislation, Italian health service,  the role of the Laboratory Technician, the organization of the laboratory and the presentation Of the different branches of Laboratory Medicine that will be treated in the following years of the Study Course.

TEACHING METHODS

Frontal lessons

SYLLABUS/CONTENT

Program Lectures Clinical Pathology I - (1 CFU) Lecturer  Dr. Michele Mussap: Analytical phases, pre-analytical, analytical post; Clinical risk management; appropriateness. Analytical Phase: Methods, Sensitivity, Precision, Repetition and Reproducibility,  Accuracy and Bias, Error, Refersibility, Analytical Goals, Analytical Quality Control, Critical Difference. Biological variability, analytical variability. Reference Ranges. Reference values: short note. IQC SIBioC Guidelines. EQAS SIBioC Guidelines. Blood venous withdrawal: recommendations. Limit of Detection and Limit of Quantitation Integrated .

Course of Clinical Pathology I (1 CFU) Program Lymphocyte Lecturer: Dr. F. Castelli Coagulation Factors; Primary hemostasis (vasopiastric phase); Secondary hemostasis (vascular phase); The "Coagulant Waterfall"; Fibrinolis; Thrombophilia and Thrombotic Risk Factors; The Emostasis And Thrombosis Laboratory: IE Level II Laboratory Tests, New Oral Anticoagulant Drugs

Course of Clinical Pathology I (1 CFU) Hematology Program Professor: Dr. Alessandro Poggi Blood: Biological Composition and Physical Physical Properties . Physiological and physiopathological  emopoiesis. Use of the microscope and analysis of the blood streak. Blood components analysis technologies. Red series and reticulocyte parameters. Anemie. Sickle cell anemia. White series: myeloid and lymphoid component. White Series Alterations. Techniques for White Series Analysis. Monoclonal Gymnopaths

Med 46 - Technical Sciences of Laboratory Medicine - Teacher Alessandra Signoretti (1 CFU): Basic Techniques Introduction to Laboratories, Analytical Process, Urine Examination, Deontological, Regulatory and Professional aspects of the Biomedical Laboratory Technician. The technological evolution in Laboratory Medicine; Professional Development of the Laboratory Technician; Health and business law; Minimum Structural and Organizational Requirements of a Laboratory; The analytical process in the Laboratory; Physical examination of urine.

 Med 46 - Technical Sciences of Laboratory Medicine (1 CFU) Lecturer: Sonia Schiavo:  Basic Techniques Donation Bag Management Techniques Organization of the Transfusion Service and the Blood Bank; Processing and production of I and II hemoconductors; Quality control of the hemoconponents; Biological validation.

 Med 46 - Technical Sciences of Laboratory Medicine (1 CFU) Lecturer: Eleonora Carlini: Pathophysiology of the blood. Physiology and of the blood of the Med Blood Laboratories - Basic Techniques Course of Hematology - Laboratory Approach to Hematic Investigations.  Hemocromocytometric examination (direct manual counts in camera and Instrumentation Automated ADVIA / COULTER), hemocromocytometric parameters and critical evaluation; Peripheral blood streak execution and M.G.G coloration evaluation of cell populations). Malaria test. VES dosage. Hemoglobin functions: HB A function and major hemoglobinopathies (Dosage: HPLC method and capillary electrophoresis), track evaluation. Examination of osmotic fragility (RGO) and G6PD dosage. Physical examination of LCR and room counting for cellular elements. Cavity Liquid Examination (Exhale, Essudate and Main Parameter Dose Examined). Full stool examination (coprochemical examination, parasite research and occult blood testing).

Med 46 - Technical Sciences of Laboratory Medicine - (1 CFU) Lecturer: Cristina Cusato:  Basic Techniques for the Management of an Urgency / Emergency Department The Emergency Laboratory; Description of an emergency laboratory; Urgent tests and their importance; Response Times; Work organization; Coagulation basis test: description of analytical methods, coagulometers; Chain of custody: legal aspects, alcohol test description and principles of the method, toxicological test description and principles of the method. Immunosuppressants Drugs and Drugs: Description of test methods and principles of the method of analysis, clinical relevance, and drug use. Emogasanalysis: description test, principles of analytical method, basic acid balance principles, Poct (point of car)

RECOMMENDED READING/BIBLIOGRAPHY

Dr. Mussap: Laboratory Medicine: Author Prof. Mario Plebani (more information from the Teacher)

Dr: Poggi: The whole course will be delivered to all students via Aulaweb. The topics discussed can be found in the following texts: Laboratory Techniques in Hemopathy Diagnosis, Vol I, Authors: Cuneo - Castoldi - Rigolin, Piccin publisher, Publication Date: November 2011, ISBN: 978-88-299-2054-9 ; Manual of Hematology, Authors: Corradini - Foa '- Boccadoro - Federici - AAVV ISBN: 9788877118165, Publisher: Minerva Medica; Blood and Emolin Phopoietic Organ Diseases by Sante Tura, VI Edition 2015, DOI: 10.15651 / 978-88-748-8884-9 Publishing Company Esculapio

TEACHERS AND EXAM BOARD

Exam Board

ELEONORA CARLINI

CRISTINA CUSATO

GILBERTO FILACI

ALESSANDRO POGGI

MARGARITA RUMBULLAKU

SONIA SCHIAVO

ALESSANDRA SIGNORETTI (President and Coordinator of Integrated Course)

LESSONS

LESSONS START

The year Second semester

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

Disciplines MED / 46 Clinical Pathology Except Dr. Mussap written test with multiple response questions to be supplemented by oral examination. Voting of the written test will be considered and calculated on the average for the final vote.

Dr. Mussap: oral test

ASSESSMENT METHODS

Students will have to demonstrate that they have acquired the fundamental concepts envisaged by each discipline, have acquired the ability to apply theory to practical models of Laboratory Medicine and have acquired the ability to use technical and scientific terminology.

Exam schedule