CODE 55413 ACADEMIC YEAR 2018/2019 CREDITS 10 cfu anno 1 FARMACIA 8452 (LM-13) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR CHIM/03 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 1° Semester PREREQUISITES Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: Pharmacy 8452 (coorte 2018/2019) PHARMACEUTICAL TECHNOLOGY, SOCIOECONOMY AND LAW II (PHAR MD) 67522 Pharmacy 8452 (coorte 2018/2019) ANALITICAL CLINICAL CHEMISTRY (PART OF I.C.)(PHAR MD) 64550 Pharmacy 8452 (coorte 2018/2019) ORGANIC CHEMISTRY 60795 Pharmacy 8452 (coorte 2018/2019) DIETETIC PRODUCTS 64191 Pharmacy 8452 (coorte 2018/2019) ANALITICAL CHEMISTRY AND ANALITICAL CLINICAL CHEMISTRY (I.C.)(PHAR MD) 64551 Pharmacy 8452 (coorte 2018/2019) PHARMACEUTICAL TECHNOLOGY SOCIOECONOMY AND LAW I (WITH PRACTICE) 67449 Pharmacy 8452 (coorte 2018/2019) ANALYSIS OF DRUGS I (LM FAR) 80318 Pharmacy 8452 (coorte 2018/2019) ANALYSIS OF DRUGS II 80322 Pharmacy 8452 (coorte 2018/2019) GENERAL MEDICINAL CHEMISTRY AND MEDICINAL CHEMISTRY I 80319 Pharmacy 8452 (coorte 2018/2019) BIOCHEMISTRY AND APPLIED BIOCHEMISTRY 80314 Pharmacy 8452 (coorte 2018/2019) PHARMACOLOGY AND PHARMACOTERAPY 80327 Pharmacy 8452 (coorte 2018/2019) GENERAL PHARMACOLOGY AND TOXICOLOGY 80324 Pharmacy 8452 (coorte 2018/2019) PHARMACOGNOSY AND PHARMACOVIGILANCE 80328 Pharmacy 8452 (coorte 2018/2019) MEDICINAL CHEMISTRY AND TOXICOLOGICAL CHEMISTRY 80337 Pharmacy 8452 (coorte 2018/2019) ANALITICAL CHEMISTRY (PART OF INTEGRATED COURSE)(PHAR MD) 64549 Pharmacy 8452 (coorte 2018/2019) COSMETIC PRODUCTS 67501 TEACHING MATERIALS AULAWEB AIMS AND CONTENT SYLLABUS/CONTENT Introduction to Chemistry. Elements, compounds and mixtures. Solutions and concentration. Rules of chemical nomenclature. Chemical reactions. Stoichiometry. Gas state. The equation of state of ideal gas. Mixtures of gases and Dalton’s law of partial pressure. The real gases and Van der Waals equation. Thermodynamics. Heat of reaction and enthalpy. Enthropy. Gibbs free energy and spontaneous reactions. Atom. Atomic structure. Atomic orbitals. Electrons and orbitals. Periodic table. Chemical bond. Ionic bond. Covalent bound. Electronegativity. Lewis structures. The VSEPR theory. Hybrid orbitals. Intermolecular forces. Liquid state and solid state. Liquids. Solids. Metallic bond. Phase transitions and phase diagrams for single-component systems. Solutions. Solubility. Ideal solution and Raoult’s law. Colligative properties. Electrolytes. Degree of dissociation. Conductivity of electrolyte solutions. Chemical kynetics. Reaction rate. Collision theory. Factors affecting the rate of reactions. Kinetic equation. Catalysis. Chemical equilibrium. Law of mass action. Equilibrium constant. Le Chatelier’s principle. Homogeneous and heterogeneous equilibrium. Acids and bases. Theories of: Arrhenius, Brønsted-Lowry and Lewis. Strength of acids and bases. Acidity of aqueous solutions: pH. pH indicators. Hydrolysis. Buffer solutions. Solubility equilibrium. Complexes. Electrochemistry. Electrodes and galvanic cells. Reduction potentials and Nernst equation. Electrolysis. Faraday’s laws. Accumulators. Inorganic chemistry. Hydrogen. Main characteristics of the elements of 1, 2, 13, 14, 15, 16, 17, 18 Groups and their most representative compounds. Characteristics of the elements of d-block and representative compounds. RECOMMENDED READING/BIBLIOGRAPHY The recommended book is: - Peter Atkins, Loretta Jones, “CHIMICA GENERALE” (Seconda edizione italiana condotta sulla terza edizione originale), Ed. Zanichelli. Other books of General and Inorganic Chemistry at university level can be used, e.g.: - Peter Atkins, Loretta Jones, “PRINCIPI DI CHIMICA”, Ed. Zanichelli - Kotz, Treichel, Townsend, Treichel “CHIMICA”, VI ed., Ed. Edises - Brown, Lemay, Bursten, Murphy, Woodward, “FONDAMENTI DI CHIMICA”, Ed. Edises - Casarin, Casella, D'Agostino, Filippi, Grandinetti, Purrello, Re, Speranza, "CHIMICA GENERALE E INORGANICA" a cura di M. Speranza, Ed. Edi-ermes - Petrucci, Herring, Madura, Bissonnette, “CHIMICA GENERALE. Principi ed applicazioni moderne" (+ complete solutions manual), Ed. Piccin TEACHERS AND EXAM BOARD GIULIANA DRAVA Ricevimento: Office hours can be useful to students who wish to discuss the material being presented in class or to ask for extra help, seeking clarification. Students can meet with Prof. Drava in her office (Di.FAR. - Dipartimento di Farmacia - Viale Cembrano, 4) all days (Monday - Friday, morning or afternoon), except for public holidays and when exams, lessons, laboratory sessions or meetings are scheduled. It is recommended to arrange an appointment by e-mail (drava@difar.unige.it) or by phone (010-3532112). Exam Board GIULIANA DRAVA (President) MONICA CASALE RICCARDO LEARDI VINCENZO MINGANTI PAOLO OLIVERI PAOLA RIANI EXAMS EXAM DESCRIPTION The exam consists of two compulsory parts: a written test followed by an oral test. The written test consists in a multiple choice test (30 questions). Correct answers are scored with a value of 1, absent or ambiguous answers with a value of zero, incorrect answers with a negative value of -0,2. So, the total score is the sum of the right answers after subtracting 0,2 for each wrong answer. The test must be completed within 60 minutes. After the correction, the participants can view their test and comment it with the professor. The minimum score to be admitted to the oral exam is 18/30. If the score is LESS THAN 12, students are not permitted to repeat the failed test in the next date, if this falls within 20 days. The oral exam is conducted by two professors of the academic staff; it covers the whole course content and it takes 30 minutes approximately, for an average student. ASSESSMENT METHODS The exam aims to assess: - the knowledge and comprehension of the discipline (test) - the acquisition of a correct scientific language; - general and specific problem-solving skills in chemistry. Exam schedule Data appello Orario Luogo Degree type Note 23/04/2019 09:30 GENOVA Scritto + Orale 17/06/2019 09:30 GENOVA Scritto + Orale 01/07/2019 09:30 GENOVA Scritto + Orale 15/07/2019 09:30 GENOVA Scritto + Orale 11/09/2019 09:30 GENOVA Scritto + Orale 20/01/2020 09:30 GENOVA Scritto + Orale 03/02/2020 09:30 GENOVA Scritto + Orale