CODE 95369 ACADEMIC YEAR 2020/2021 CREDITS 4 cfu anno 3 BIOTECNOLOGIE 8756 (L-2) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/04 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester TEACHING MATERIALS AULAWEB AIMS AND CONTENT LEARNING OUTCOMES Plants as source of active compounds. GMO and production of biological activity compounds. Characteristics of the main expression systems for the production of heterologous proteins in microorganisms, animals and plants. Stable and transient genetic transformation; Nuclear transformation; Plastidic transformation. Optimization of expression of heterologous proteins in plant systems. PGM recombinant drugs. Production of vaccines in plant systems. Plants as bioreactors for the production of active molecules. Molecular pharming and molecular farming. SYLLABUS/CONTENT Plants as source of active compounds. GMO and production of biological activity compounds. Characteristics of the main expression systems for the production of heterologous proteins in microorganisms, animals and plants. Stable and transient genetic transformation; Nuclear transformation; Plastidic transformation. Optimization of expression of heterologous proteins in plant systems. PGM recombinant drugs. Production of vaccines in plant systems. Plants as bioreactors for the production of active molecules. Molecular pharming and molecular farming. TEACHERS AND EXAM BOARD MARIA ANGELA MIELE Exam Board MARIA ANGELA MIELE (President) TULLIO FLORIO CHIARA GENTILI LESSONS Class schedule MOLECULAR PHARMING