The course titled "Biology II" aims to integrate the knowledge of "functional histology" and cell biology by aiming to provide students with knowledge about the organization and function of cells and human tissues with particular attention to the connection between morphology and function.
Know structure, organization and function of different human tissues and morphological-functional characteristics of cells that compose them.
In order to provide the student with a complete view of the tissue organization, basic and advanced methods for analyzing the organization of human tissues and how this organization is instrumental in ensuring full homeostatic tissue function are discussed.
The course thus aims at:
1. provide basic concepts on morphology, cellular and molecular organization of human tissues;
2. discuss in depth the cellular and molecular characteristics of the different stem cell populations in the various tissues;
3. describe the functional properties of the various tissues and cells that compose them, focusing on physiopathological aspects as well.
It is possible that the method of conducting the lessons is changed due to emergency situations that prevent the performance of the lessons in attendance. In this case the lessons will be carried out through the Teams platform using suitable replacement teaching tools. For the practical part, high resolution slide images and / or virtual microscope will be used.
General knowledge of chemistry, biology and genetics
Class teaching and practical exercises under an optical microscope and laboratory.
EUKARYOTIC CELL:
The main steps in eukaryotic cell evolution
The plasma membrane:
Structure and functions
Membrane transports
Endocytosis and esocytosis
The cytoplasm:
Hyaloplasm
Ribosomes
Rough-surfaced endoplasmic reticulum (RER)
Smooth-surfaced endoplasmic reticulum (REL)
Golgi apparatus
Lysosomes
Peroxisomes
Mitochondria
The cytoskeleton
Cell movement
Cell motility and intracellular transport
Cell junctional comlexes
The nucleous
The nucleolus
Cell cycle and mitosis
TISSUES:
Epithelial tissue:
Main characteristics of epithelia
Lining epithelia: organization and classification
Structural surface differentiations of epithelial cells (microvilli, stereocilia, cilia)
Secretory epithelia:
• exocrine glands
• endocrine glands
Connective tissue:
Extracellular matrix:
• fibers
• ground substance
Cell components of connective tissue
Connective tissue proper
Support connective tissue: cartilage and bone tissue
Ossification
Trophic connective tissue: blood and lymph
Lymphatic tissue
Cells of the innate and adaptive immune system
Muscle tissue:
Myofibril structure and muscle contraction
Nerve tissue:
Istologia di Monesi 7° edizione Casa Editrice Piccin
Citologia, Istologia e Anatomia Microscopica a cura di D. Zaccheo e M. Pestarino Casa Editrice Pearson
Atlante on-line (accesso libero): http://www.istologia.unige.it/
Istologia (testo e atlante) di M.H. Ross e W. Pawlina Casa Editrice Ambrosiana
Ricevimento: By appointment by email: roberta.castriconi@unige.it
Ricevimento: By appointment by e-mail: emanuela.marcenaro@unige.it
Ricevimento: Student reception by appointment, contact the teacher via e-mail: mariella.dellachiesa@unige.it
ROBERTA CASTRICONI (President)
EMANUELA MARCENARO (President)
MARIELLA DELLA CHIESA
ALESSANDRA DONDERO
SILVIA PESCE
March 2020
Practical test and oral examination
The examamination includes two tests.
The first consists of a practical test where the student must describe two histological preparations by the use of optical microscope.
The second test, performing only upon the positive evaluation of the first test, consists of an oral examination that is subordinated to passing the practical test and which includes cytology questions and histology questions concerning the teaching content.
It is possible that emergency situations prevent the students to taking part in the examination in attendance for the final evaluation. In this case, the Teams platform will be used. For the practical test, the recognition and description of histological preparations. will be carried out on tissue images proposed through the Teams platform.
