CODE 101966 ACADEMIC YEAR 2020/2021 CREDITS 10 cfu anno 1 BIOTECNOLOGIE 8756 (L-2) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR BIO/17 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 2° Semester PREREQUISITES Propedeuticità in uscita Questo insegnamento è propedeutico per gli insegnamenti: Biotechnology 8756 (coorte 2020/2021) CELLULAR AND DEVELOPMENTAL BIOLOGY AND LABORATORY OF CELLULAR CULTURES AND DEVELOPMENTAL BIOLOGY 66910 Biotechnology 8756 (coorte 2020/2021) MICROBIOLOGIA PATOLOGIA GENERALE IMMUNOLOGIA E LABORATORIO 66902 TEACHING MATERIALS AULAWEB OVERVIEW The course titled "Biology II" aims to integrate the knowledge of "functional histology" and cell biology by aiming to provide students with knowledge about the organization and function of cells and human tissues with particular attention to the connection between morphology and function. AIMS AND CONTENT LEARNING OUTCOMES Know structure, organization and function of different human tissues and morphological-functional characteristics of cells that compose them. AIMS AND LEARNING OUTCOMES In order to provide the student with a complete view of the tissue organization, basic and advanced methods for analyzing the organization of human tissues and how this organization is instrumental in ensuring full homeostatic tissue function are discussed. The course thus aims at: 1. provide basic concepts on morphology, cellular and molecular organization of human tissues; 2. discuss in depth the cellular and molecular characteristics of the different stem cell populations in the various tissues; 3. describe the functional properties of the various tissues and cells that compose them, focusing on physiopathological aspects as well. It is possible that the method of conducting the lessons is changed due to emergency situations that prevent the performance of the lessons in attendance. In this case the lessons will be carried out through the Teams platform using suitable replacement teaching tools. For the practical part, high resolution slide images and / or virtual microscope will be used. PREREQUISITES General knowledge of chemistry, biology and genetics TEACHING METHODS Class teaching and practical exercises under an optical microscope and laboratory. SYLLABUS/CONTENT EUKARYOTIC CELL: The main steps in eukaryotic cell evolution The plasma membrane: Structure and functions Membrane transports Endocytosis and esocytosis The cytoplasm: Hyaloplasm Ribosomes Rough-surfaced endoplasmic reticulum (RER) Smooth-surfaced endoplasmic reticulum (REL) Golgi apparatus Lysosomes Peroxisomes Mitochondria The cytoskeleton Cell movement Cell motility and intracellular transport Cell junctional comlexes The nucleous The nucleolus Cell cycle and mitosis TISSUES: Epithelial tissue: Main characteristics of epithelia Lining epithelia: organization and classification Structural surface differentiations of epithelial cells (microvilli, stereocilia, cilia) Secretory epithelia: • exocrine glands • endocrine glands Connective tissue: Extracellular matrix: • fibers • ground substance Cell components of connective tissue Connective tissue proper Support connective tissue: cartilage and bone tissue Ossification Trophic connective tissue: blood and lymph Lymphatic tissue Cells of the innate and adaptive immune system Muscle tissue: striated skeletal and cardiac muscle smooth muscle tissue Myofibril structure and muscle contraction Nerve tissue: neurons glial cells nerve fibers synapses and impulse transmission RECOMMENDED READING/BIBLIOGRAPHY Istologia di Monesi 7° edizione Casa Editrice Piccin Citologia, Istologia e Anatomia Microscopica a cura di D. Zaccheo e M. Pestarino Casa Editrice Pearson Atlante on-line (accesso libero): http://www.istologia.unige.it/ Istologia (testo e atlante) di M.H. Ross e W. Pawlina Casa Editrice Ambrosiana TEACHERS AND EXAM BOARD ROBERTA CASTRICONI Ricevimento: By appointment by email: roberta.castriconi@unige.it EMANUELA MARCENARO Ricevimento: By appointment by e-mail: emanuela.marcenaro@unige.it MARIELLA DELLA CHIESA Ricevimento: Student reception by appointment, contact the teacher via e-mail: mariella.dellachiesa@unige.it ALESSANDRA DONDERO Exam Board ROBERTA CASTRICONI (President) EMANUELA MARCENARO (President) MARIELLA DELLA CHIESA ALESSANDRA DONDERO SILVIA PESCE LESSONS LESSONS START March 2020 Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION Practical test and oral examination ASSESSMENT METHODS The examamination includes two tests. The first consists of a practical test where the student must describe two histological preparations by the use of optical microscope. The second test, performing only upon the positive evaluation of the first test, consists of an oral examination that is subordinated to passing the practical test and which includes cytology questions and histology questions concerning the teaching content. It is possible that emergency situations prevent the students to taking part in the examination in attendance for the final evaluation. In this case, the Teams platform will be used. For the practical test, the recognition and description of histological preparations. will be carried out on tissue images proposed through the Teams platform. Exam schedule Data appello Orario Luogo Degree type Note 21/01/2021 09:30 GENOVA Scritto 21/01/2021 10:00 GENOVA Scritto + Orale 17/02/2021 10:00 GENOVA Scritto + Orale 18/02/2021 09:30 GENOVA Scritto 21/06/2021 09:30 GENOVA Scritto 14/07/2021 09:30 GENOVA Scritto 17/09/2021 09:30 GENOVA Scritto