CODE 67952 ACADEMIC YEAR 2020/2021 CREDITS 2 cfu anno 2 OSTETRICIA 9278 (L/SNT1) - GENOVA SCIENTIFIC DISCIPLINARY SECTOR MED/04 LANGUAGE Italian TEACHING LOCATION GENOVA SEMESTER 1° Semester MODULES Questo insegnamento è un modulo di: GENERAL PATHOLOGY AND INTERNAL MEDICINE TEACHING MATERIALS AULAWEB OVERVIEW The General Pathology and Immunology Science are a multidisciplinary sciences relating to human health: how and why it happens the health disturbance, it includes the molecular and cellular mechanisms that underlie the disease, ie etiopathogenesis and all aspects of the host defenses against infection. AIMS AND CONTENT AIMS AND LEARNING OUTCOMES The course aims to train experts in the field of midwifery. The course aims to provide a specific basis for basic materials needed for the student's education. The student will learn the fundamental skills necessary for the understanding of the biological basis and principal pathophisiology concepts of the General Pathology and Immunology presented during the course. TEACHING METHODS Frontal lectures. The course consists of 24 hours of training activities, lectures on the topics of the program. It is required at least 75% of the hours of frontal lectures. SYLLABUS/CONTENT 1. CELLULAR PATHOLOGY: pathogenesis of atherosclerosis 2. PROCESS OF DEFENSE: Inflammation: Phases, classification main types of acute inflammation, inflammation interstitial and granulomatous 3. CANCER Metaplasia, dysplasia, anaplasia Classification and malignant characters staging systems and gradation chemical carcinogenesis, physical and biological Metabolism and activation of carcinogens Initiation, promotion, progression Invasiveness and metastasis Oncogenes and tumor suppressor Outline of tumor markers. OVERVIEW OF THE IMMUNE SYSTEM - Cells and Organs of Immune System - Adaptive Immunity GENERATION OF B-CELL AND T CELL RECEPTORS - Antigens and Antibody - Organization and Expression of Immunoglobulin Genes - The Major Histocompatibility Complex - T-Cell Receptor - T-Cell Generation - T-Cell Activation and Differentiation - B-Cell Generation, Activation and Differentiation IMMUNE EFFECTOR MECHANISMS - Cytokines and Chemokines - The Complement System - Cell-Mediated Effector Responses - Hypersensitive Reactions IMMUNE SYSTEM IN HEALTH AND DISEASES - Tolerance and Autoimmunity - The immune system in pregnancy RECOMMENDED READING/BIBLIOGRAPHY Didattic resources presented by teacher during the lessons -G.M.Pontieri :Patologia generale & fisiopatologia generale per i corsi di laurea in Professioni Sanitarie. Piccin ed. -G.Barrera, R.A. Canuto, C.Gardi, G. Muzio,M.Nitti, A.Pompella: Patologia e fisiopatologia generale. Monduzzi ed. -Licastro-Caruso: Compendio di patologia generale. Casa editrice Ambrosiana -G.M. Pontieri: Elementi di Patologia e Fisiopatologia Generale, III edizione, Piccin ed. -M. Parola:Patologia Generale, Edises ed. -Maier J., Mariotti M.:Elementi di Patologia Generale e Fisiopatologia, Minisito ed. -Poli G., Columbano A.: Compendio di Patologia Generale e Fisiopatologia, Minerva Medica ed. Kuby: Immunologia. UTET ed. For further advice please contact the teacher. TEACHERS AND EXAM BOARD CRISTINA BOTTINO Ricevimento: By appointment Email: Cristina.Bottino@unige.it Exam Board EZIO FULCHERI (President) SIMONE NEGRINI GABRIELLA PIATTI CRISTINA BOTTINO (President and Coordinator of Integrated Course) LESSONS Class schedule The timetable for this course is available here: Portale EasyAcademy EXAMS EXAM DESCRIPTION - Oral test or written test Multiple Choice. ASSESSMENT METHODS The assessment takes place only through the final exam which aims to ensure the effective acquisition by the student of the expected learning outcomes. In order to pass the exam (vote of not less than 18/30) the student must demonstrate that: - Know the principal topics - Be able to reason by connecting the various topics, - Demonstrate ability to transverse and critically deal with the required arguments; - Adoption of appropriate terminology. Exam schedule Data appello Orario Luogo Degree type Note 14/01/2021 10:00 GENOVA Orale 18/02/2021 10:00 GENOVA Orale 17/06/2021 10:00 GENOVA Orale 15/07/2021 10:00 GENOVA Orale 16/09/2021 10:00 GENOVA Orale