OVERVIEW

The drug-discovery process as well as the structure-activity relationships of the different classes of chemotherapeutic agents and hormones (peptide and steroidal) are presented in the course

AIMS AND CONTENT

AIMS AND LEARNING OUTCOMES

The course aims at presenting the relevant approaches currently used in the drug discovery process and the structure-activity relationships developed for chemotherapeutic agents (i.e. antibacterial, antiviral and antitumor agents) and for steroidal/peptide hormones. This knowledge is part of the cultural background characterizing a pharmacist as an healthcare professional.

TEACHING METHODS

Lectures

SYLLABUS/CONTENT

The first part of the course is focussed on the drug discovery process with particular emphasis on computer aided drug design and combinatorial chemistry.

The second part deals with the synthetic strategies, the structure-activity relationships and the pharmacokinetic/pharmacodynamic properties of different classes of chemotherapeutic drugs (e.g. antibacterial, antiprotozoal, antimycotic, antiviral and antitumor agents) and steroidal/peptide hormones.

RECOMMENDED READING/BIBLIOGRAPHY

Foye's. Principi di chimica farmaceutica. Piccin

Wilson & Gisvold. Chimica Farmaceutica. Casa Editrice Ambrosiana

Gasco, Gualtieri, Melchiorre. Chimica faramceutica. Casa Editrice Ambrosiana

TEACHERS AND EXAM BOARD

Exam Board

ANDREA SPALLAROSSA (President)

CHIARA BRULLO

FRANCESCA MUSUMECI

SILVIA SCHENONE

BRUNO TASSO

LESSONS

Class schedule

The timetable for this course is available here: Portale EasyAcademy

EXAMS

EXAM DESCRIPTION

Viva oral examination

ASSESSMENT METHODS

The exam is directed to the evaluation of the learning, the communicative and problem-solving skills of the student

Exam schedule